Figure 9.
Examples of interesting observations from this project. (a-d) Three adjacent Brachyury/T-box genes - (a) CG5093, (b) CG5107, (c) Dorsocross - show remarkably similar expression patterns at cellular blastoderm and are located
next to each other on the chromosome (d). (e-i) Expression patterns of five genes with homology to metabolic and detoxification enzymes:
(e) hydroxyacylglutathione hydrolase, CG9026; (f) cytochrome P450, Cyp310a; (g) multi-drug resistance gene, Mdr49; (h) xanthine dehydrogenase, rosy; and (i) transketolase, CG8036. (j) Dorsal view of a stage-8 embryo stained with a probe that reveals apically localized
mRNAs (CG18375) within the developing hindgut epithelium, contrasted with basally localized mRNA
(CG11207) in the same cells (k). (l) Close-up of (j) highlighting the apically localized mRNA in the epithelium surrounding
the invaginating hindgut pocket with pole cells (pc). A single epithelial cell is
outlined. (m) Close-up of (K) revealing an equivalent region of an embryo as (l) and highlighting
the basally localized mRNA. (n) Portion of the dorsal side of a pre-blastoderm embryo stained for mRNA (CG1962) that appears to be localized to an unidentified subnuclear compartment. (o) Close-up of five nuclei from (n).
Tomancak et al. Genome Biology 2002 3:research0088.1 doi:10.1186/gb-2002-3-12-research0088 |