Table 1 |
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The six conserved eukaryotic core SMC proteins |
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| SMC1 |
SMC2 |
SMC3 |
SMC4 |
SMC5 |
SMC6 |
|
|
|
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| Protein length (in amino acids) |
1233 |
1197 |
1217 |
1288 |
1101 |
1091 |
| Accession number |
AAB34405 |
XP_050024 |
AAC14893 |
BAA73535 |
CAC39247 |
CAC39248 |
| Locus* |
Xp11.22-p11.21 |
9q22.31-q22.33 |
10q25 |
3q26.1 |
9q12 |
2p23-24 |
| Homologs: |
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| S. cerevisae |
SMC1 |
SMC2 |
SMC3 |
SMC4 |
YOL034w |
RHC18 |
| S. pombe |
psm1 |
cut14 |
psm3 |
cut3 |
spr18 |
rad18 |
| C. elegans |
T34063 |
Mix1 |
T31550 |
T21809 |
AAK31464 |
CAB16920 |
| D. melanogaster |
AAF56231 |
AAF58197 |
dCAP |
Gluon |
AAF51749 |
AAF56254 |
| Xenopus laevis |
XSMC1 |
XCAP-E |
XSMC3 |
XCAP-C |
- |
- |
| Mus musculus |
SmcB |
- |
SmcD |
- |
- |
SMC6 |
| A. thaliana |
CAB77587 |
TITAN3 |
AAD26882 |
BAB10693 |
T51375 |
MIM |
|
|
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The length of the human proteins, their GenBank accession numbers and map positions are shown at the top of the table. *Mapping data for SMC1-SMC4 is from the Map Viewer at the National Center for Biotechnology Information (NCBI) [24], and for SMC5 and SMC6 is from [8]. Homologs from a range of species are shown below the data for human SMCs. Characterized genes are in italics, and the accession numbers of related proteins from genome sequence data found by BLAST searching are included; - indicates that no sequence has been found. |
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|
Harvey et al. Genome Biology 2002 3:reviews3003.1 doi:10.1186/gb-2002-3-2-reviews3003 |
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