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All you need to know about p53

Eliezer Kopf

  • Correspondence: Eliezer Kopf

Author Affiliations

Genome Biology 2002, 3:reports2010  doi:10.1186/gb-2002-3-2-reports2010


The electronic version of this article is the complete one and can be found online at: http://genomebiology.com/2002/3/2/reports/2010


Received:11 December 2001
Published:1 February 2002

© 2002 BioMed Central Ltd

Content

For researchers interested in tumor suppressors, and in particular the p53 protein, this is a useful website; it includes a p53 database, an APC database and a p53 mutation-analysis database. Several aspects of p53 biology are also summarized, such as 'the p53 story' (''everything you want to know about p53 but you never bother to ask''), the anatomy of the gene and its phylogeny, and its mutation in tumors. The site also includes data on other proteins involved in the biology of p53, such as MDM2 and p73. There is information on scientists in the field, links to other sites with p53 information, and a large list of monoclonal antibodies against p53.

Navigation

This is a well organized and presented site with large amounts of information, some of which can be easily downloaded in Word or Excel format.

Reporter's comments

Timeliness

Last updated in December 2001.

Best feature

The list of anti-p53 antibodies is particularly useful.

Worst feature

The list of job opportunities is quite short.

Wish list

A search engine from the home page would help to locate information.

Related websites

Michael Tainsky's homepage has information on p53 and other oncogenes.

Table of links

Assumptions made about all sites unless otherwise specified:
The site is free, in English and no registration is required. It is relatively quick to download, can be navigated by an 'intermediate' user, and no problems with connection were found. The site does not stipulate that any particular browser be used and no special software/plug-ins are required to view the site. There are relatively few gratuitous images and each page has its own URL, allowing it to be bookmarked.