Genome Biology

official impact factor 6.89

Open Access Highly Access

Selection in the evolution of gene duplications

Fyodor A Kondrashov*, Igor B Rogozin, Yuri I Wolf and Eugene V Koonin

Genome Biology 2002, 3:research0008-research0008.9 doi:10.1186/gb-2002-3-2-research0008

Accesses  

  • Last 30 days: 111 accesses
  • Last year: 1257 accesses
  • All time: 18949 accesses

Cited by

BioMed Central: 31 citations

Research article   Open Access

Rates of evolution in stress-related genes are associated to habitat preference in two Cardamine lineages

Lino Ometto, Mingai Li, Luisa Bresadola, Claudio Varotto BMC Evolutionary Biology 2012, 12:7 (18 January 2012)

Proceedings   Open Access

Identification of conserved gene clusters in multiple genomes based on synteny and homology

Anasua Sarkar, Hayssam Soueidan, Macha Nikolski BMC Bioinformatics 2011, 12(Suppl 9):S18 (5 October 2011)

Research article   Open Access

Local synteny and codon usage contribute to asymmetric sequence divergence of Saccharomyces cerevisiae gene duplicates

Lijing Bu, Ulfar Bergthorsson, Vaishali Katju BMC Evolutionary Biology 2011, 11:279 (28 September 2011)

Research article   Open Access

Gene socialization: gene order, GC content and gene silencing in Salmonella

Nikolas Papanikolaou, Kalliopi Trachana, Theodosios Theodosiou, Vasilis J Promponas, Ioannis Iliopoulos BMC Genomics 2009, 10:597 (11 December 2009)

Research article   Open Access

Expansion of tandem repeats in sea anemone Nematostella vectensis proteome: A source for gene novelty?

Guy Naamati, Menachem Fromer, Michal Linial BMC Genomics 2009, 10:593 (10 December 2009)

Research article   Open Access

Does negative auto-regulation increase gene duplicability?

Tobias Warnecke, Guang-Zhong Wang, Martin J Lercher, Laurence D Hurst BMC Evolutionary Biology 2009, 9:193 (7 August 2009)

Research article   Open Access Highly Accessed

Phylogeny and evolution of Rab7 and Rab9 proteins

Paweł Mackiewicz, Elżbieta Wyroba BMC Evolutionary Biology 2009, 9:101 (14 May 2009)

Research article   Open Access Highly Accessed

The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Rosario Angelica, Marina Scalia, Luisa Statello, Loredana Salito, Luisa Tomasello, Salvo Pernagallo, Salvo Valenti, Vito D'Agostino, Patrizio Triberio, Igor Tandurella, Giuseppe A Palumbo, Piera La Cava, Viviana Cafiso, Taschia Bertuccio, Maria Santagati, Giovanni Li Destri, Salvatore Lanzafame, Francesco Di Raimondo, Stefania Stefani, Bud Mishra, Michele Purrello BMC Medical Genomics 2009, 2:20 (30 April 2009)

Research article   Open Access Highly Accessed

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom

Lukasz Huminiecki, Leon Goldovsky, Shiri Freilich, Aristidis Moustakas, Christos Ouzounis, Carl-Henrik Heldin BMC Evolutionary Biology 2009, 9:28 (3 February 2009)

Software article   Open Access

Syntenator: Multiple gene order alignments with a gene-specific scoring function

Christian Rödelsperger, Christoph Dieterich Algorithms for Molecular Biology 2008, 3:14 (6 November 2008)

Research article   Open Access Highly Accessed

Unique genes in plants: specificities and conserved features throughout evolution

David Armisén, Alain Lecharny, Sébastien Aubourg BMC Evolutionary Biology 2008, 8:280 (10 October 2008)

Research article   Open Access

Evolutionary analysis of the highly dynamic CHEK2 duplicon in anthropoids

Claudia Münch, Stefan Kirsch, António MG Fernandes, Werner Schempp BMC Evolutionary Biology 2008, 8:269 (2 October 2008)

Commentary   Open Access Highly Accessed

MalVac: Database of malarial vaccine candidates

Rupanjali Chaudhuri, Shakil Ahmed, Faraz Ansari, Harinder Singh, Srinivasan Ramachandran Malaria Journal 2008, 7:184 (23 September 2008)

A web server has been developed to facilitate the identification of probable vaccine candidates: it can be freely accessed.

Research article   Open Access

The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements

Tomàs Marques-Bonet, Ze Cheng, Xinwei She, Evan E Eichler, Arcadi Navarro BMC Genomics 2008, 9:384 (12 August 2008)

Research article   Open Access

Duplicate gene evolution and expression in the wake of vertebrate allopolyploidization

Frédéric JJ Chain, Dora Ilieva, Ben J Evans BMC Evolutionary Biology 2008, 8:43 (8 February 2008)

In frog species that have undergone allopolyploidization, gene expression levels of duplicate genes often diverge quickly in spite of strong initial purifying selection, giving insight in to the evolutionary mechanisms that occur after genome duplication in vertebrates.

Research article   Open Access

Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene

Maayan Amit, Noa Sela, Hadas Keren, Ze'ev Melamed, Inna Muler, Noam Shomron, Shai Izraeli, Gil Ast BMC Molecular Biology 2007, 8:109 (29 November 2007)

Exonization of transposed elements is higher within duplicated genes, implying that duplicates of the transcription initiation factor gene TIF-1A, for example, are free from the evolutionary constraints on single-copy genes.

Research article   Open Access

Persistence of duplicated PAC1 receptors in the teleost, Sparus auratus

João CR Cardoso, Edwin CJM de Vet, Bruno Louro, Greg Elgar, Melody S Clark, Deborah M Power BMC Evolutionary Biology 2007, 7:221 (12 November 2007)

Research   Open Access Highly Accessed

All duplicates are not equal: the difference between small-scale and genome duplication

Luke Hakes, John W Pinney, Simon C Lovell, Stephen G Oliver, David L Robertson Genome Biology 2007, 8:R209 (4 October 2007)

The comparison of pairs of gene duplications generated by small-scale duplications with those created by large-scale duplications shows that they differ in quantifiable ways. It is suggested that this is directly due to biases on the paths to gene retention rather than association with different functional categories.

Research article   Open Access Highly Accessed

A genome-wide survey of changes in protein evolutionary rates across four closely related species of Saccharomyces sensu stricto group

Yoshihiro Kawahara, Tadashi Imanishi BMC Evolutionary Biology 2007, 7:9 (29 January 2007)

Research   Open Access

Relating tissue specialization to the differentiation of expression of singleton and duplicate mouse proteins

Shiri Freilich, Tim Massingham, Eric Blanc, Leon Goldovsky, Janet M Thornton Genome Biology 2006, 7:R89 (9 October 2006)

An analysis of the relationship between duplication events, the time they took place and the expression breadth of the duplicated genes supports the subfunctionalization model, in which expression divergence following gene duplication promotes the retention of a gene in multicellular species.

Research   Open Access Highly Accessed

Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution

Julia Tischler, Ben Lehner, Nansheng Chen, Andrew G Fraser Genome Biology 2006, 7:R69 (2 August 2006)

High-throughput combinatorial RNAi demonstrates that many duplicated genes in C. elegans can retain redundant functions for more than 80 million years

Research article   Open Access Highly Accessed

Fast rate of evolution in alternatively spliced coding regions of mammalian genes

Ekaterina O Ermakova, Ramil N Nurtdinov, Mikhail S Gelfand BMC Genomics 2006, 7:84 (18 April 2006)

A comparison of orthologous human and mouse genes indicates that alternatively spliced exons tend to have a faster rate of evolution than constitutive exons, with the rate of both synonymous and nonsynonymous substitutions increased.

Research   Open Access Highly Accessed

Nonrandom divergence of gene expression following gene and genome duplications in the flowering plant Arabidopsis thaliana

Tineke Casneuf, Stefanie De Bodt, Jeroen Raes, Steven Maere, Yves Van de Peer Genome Biology 2006, 7:R13 (20 February 2006)

Analysis of expression data of duplicated genes in Arabidopsis thaliana shows that the mode of duplication, the time since duplication and the function of the duplicated genes play a role in the divergence of their expression.

Research article   Open Access Highly Accessed

Rapid and asymmetric divergence of duplicate genes in the human gene coexpression network

Wen-Yu Chung, Reka Albert, Istvan Albert, Anton Nekrutenko, Kateryna D Makova BMC Bioinformatics 2006, 7:46 (27 January 2006)

When genes duplicate, they quickly diverge, losing shared coexpressed partners and acquiring different new partners according to a human coexpression network analysis that utilized tissue-specific microarray data.

Research article   Open Access

Duplicated genes evolve slower than singletons despite the initial rate increase

I King Jordan, Yuri I Wolf, Eugene V Koonin BMC Evolutionary Biology 2004, 4:22 (6 July 2004)

Following gene duplication there is a period of rapid evolution, which then slows down in cases where the original gene has an important biological function and the duplicate is retained.

Software   Open Access

FRAGS: estimation of coding sequence substitution rates from fragmentary data

Estienne C Swart, Winston A Hide, Cathal Seoighe BMC Bioinformatics 2004, 5:8 (29 January 2004)

Research   Open Access

Different evolutionary patterns between young duplicate genes in the human genome

Peng Zhang, Zhenglong Gu, Wen-Hsiung Li Genome Biology 2003, 4:R56 (1 September 2003)

Duplicate genes tend to evolve in different patterns following the duplication event. One copy evolves faster than the other and accumulates amino-acid substitutions evenly across the sequence, whereas the other copy evolves more slowly and accumulates amino-acid substitutions unevenly across the sequence.

Research   Open Access

Duplication is more common among laterally transferred genes than among indigenous genes

Sean D Hooper, Otto G Berg Genome Biology 2003, 4:R48 (11 July 2003)

Using both a compositional method and a gene-tree approach, a number of proposed laterally transferred genes have been identified and their nucleotide composition and frequency of duplication studied.

Research   Open Access Highly Accessed

Recent segmental and gene duplications in the mouse genome

Joseph Cheung, Michael D Wilson, Junjun Zhang, Razi Khaja, Jeffrey R MacDonald, Henry HQ Heng, Ben F Koop, Stephen W Scherer Genome Biology 2003, 4:R47 (9 July 2003)

BLAST-based computational heuristics were used to identify large and recent segmental duplications in the mouse genome sequence. Here a database of recently duplicated regions of the mouse genome is presented.

Minireview   Free

Tracking adaptive evolutionary events in genomic sequences

David A Liberles, Marta L Wayne Genome Biology 2002, 3:reviews1018-reviews1018.4 (29 May 2002)

Minireview   Free

Selection and gene duplication: a view from the genome

Andreas Wagner Genome Biology 2002, 3:reviews1012-reviews1012.3 (15 April 2002)