Figure 1.

Synonymous and nonsynonymous substitution rates for (a,b) paralogs and (c,d) orthologs from (a,c) bacteria and (b,d) mammals. All points with K_s > 0.5 (approaching saturation) were assigned a K_s value of 0.5. In (b), the blue circles represent human duplicated genes and the red circles show duplicated genes from mouse and rat. In (d), the blue circles are human-rodent orthologous comparisons, and the red circles are the mouse-rat comparisons.