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Model-based cluster analysis of microarray gene-expression data

Wei Pan*, Jizhen Lin and Chap T Le

Genome Biology 2002, 3:research0009-research0009.8 doi:10.1186/gb-2002-3-2-research0009

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How many replicates of arrays are required to detect gene expression changes in microarray experiments? A mixture model approach

Wei Pan, Jizhen Lin, Chap T Le Genome Biology 2002, 3:research0022-research0022.10 (22 April 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

The question of how many replicates are required to detect differentially expressed genes in microarray experiments has barely been addressed. Here, the issue of how to calculate the number of replicates in the context of applying a nonparametric statistical method is discussed.

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