Genome Biology

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Deposited research article

Using orthologous and paralogous proteins to identify specificity determining residues

Leonid A Mirny1* and Mikhail S Gelfand2

Author Affiliations

1 Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, 77 Massachusetts ave, Cambridge, MA 02139

2 IntegratedGenomics-Moscow, P.O.Box 348, Moscow, 117333, Russia

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Genome Biology 2002, 3:preprint0002-preprint0002.20 doi:10.1186/gb-2002-3-3-preprint0002


This is the first version of this article to be made available publicly, and no other version is available at present.

Published: 19 February 2002

Additional files

Additional data file 1:

Detailed description of the methods used to compute statistical significance and a table of specificity determining amino acids in other proteins of LacI family

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