Table 1 |
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Cell-cycle regulatory proteins mentioned in this article |
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Name of protein |
Names of homologs |
Enzymatic function |
Cell-cycle function |
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Bfa1 |
GTPase-activating protein |
Mitotic exit |
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Bub2 |
Checkpoint component |
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BubR1 |
Spindle-assembly checkpoint component |
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Bub3 |
Spindle-assembly checkpoint component |
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Cdc20 |
Activator of the anaphase-promoting complex (APC) |
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Cdc25 |
Phosphatase |
Activates cyclin-dependent kinase (Cdc2) |
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Cdc5 |
Polo-like protein kinase |
Mitotic exit |
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Cdh1 |
Activator of the anaphase-promoting complex (APC) |
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Centriolin |
Centrosome component |
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Chk1 |
Protein kinase |
Checkpoint component |
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Emi1 |
Inhibitor of the anaphase-promoting complex (APC) |
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Ipl1 |
Aurora-like protein kinase |
Spindle-assembly checkpoint component |
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Kendrin |
Pericentrin* |
Centrosome component |
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Mad2 |
Checkpoint component |
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Mik1 |
Protein kinase |
Inactivates cyclin-dependent kinase (Cdc2) |
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Mps1 |
Protein kinase |
Spindle-assembly checkpoint component |
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Rad24 |
14-3-3 |
DNA-damage checkpoint component |
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Skp1 |
Component of a ubiquitin ligase complex, the SCF |
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Tem1 |
Ras-related GTPase |
Mitotic exit |
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γ tubulin |
Centrosome component |
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Wee1 |
Protein kinase |
Inactivates cyclin-dependent kinase (Cdc2) |
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* Pericentrin is a smaller isoform of kendrin. |
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Bhalla Genome Biology 2002 3:reports4009.1 doi:10.1186/gb-2002-3-4-reports4009 |
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