Table 1

Cell-cycle regulatory proteins mentioned in this article

Name of protein

Names of homologs

Enzymatic function

Cell-cycle function


Bfa1

GTPase-activating protein

Mitotic exit

Bub2

Checkpoint component

BubR1

Spindle-assembly checkpoint component

Bub3

Spindle-assembly checkpoint component

Cdc20

Activator of the anaphase-promoting complex (APC)

Cdc25

Phosphatase

Activates cyclin-dependent kinase (Cdc2)

Cdc5

Polo-like protein kinase

Mitotic exit

Cdh1

Activator of the anaphase-promoting complex (APC)

Centriolin

Centrosome component

Chk1

Protein kinase

Checkpoint component

Emi1

Inhibitor of the anaphase-promoting complex (APC)

Ipl1

Aurora-like protein kinase

Spindle-assembly checkpoint component

Kendrin

Pericentrin*

Centrosome component

Mad2

Checkpoint component

Mik1

Protein kinase

Inactivates cyclin-dependent kinase (Cdc2)

Mps1

Protein kinase

Spindle-assembly checkpoint component

Rad24

14-3-3

DNA-damage checkpoint component

Skp1

Component of a ubiquitin ligase complex, the SCF

Tem1

Ras-related GTPase

Mitotic exit

γ tubulin

Centrosome component

Wee1

Protein kinase

Inactivates cyclin-dependent kinase (Cdc2)


* Pericentrin is a smaller isoform of kendrin.

Bhalla Genome Biology 2002 3:reports4009.1-reports4009.4   doi:10.1186/gb-2002-3-4-reports4009