Table 1

Top-ranked 50 genes (25 pairs) for ALL/AML class separation using AP (all pairs) ranking

Pair rank

Gene ID

Pair t-score

Gene t-score

Gene rank

Gene annotation

1

M84526_at

16.16

12.88

1

DF D component of complement (adipsin)

1

M92287_at

16.16

8.87

6

CCND3 Cyclin D3

2

M23197_at

15.43

11.72

2

CD33 CD33 antigen (differentiation antigen)

2

M31523_at

15.43

11.0

3

TCF3 Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

3

U46499_at

13.56

9.14

5

Glutathione S-transferase, microsomal

3

M31303_rna1_at

13.56

6.52

36

Oncoprotein 18 (Op18) gene

4

M63138_at

13.53

9.46

4

CTSD Cathepsin D (lysosomal aspartyl protease)

4

HG1612-HT1612_at

13.53

8.47

10

Macmarcks

5

X62320_at

12.58

8.38

11

GRN Granulin

5

Z14982_rna1_at

12.58

5.54

93

MHC-encoded proteasome subunit gene LAMP7-E1 (LMP7)

6

M31211_s_at

12.41

8.61

9

MYL1 Myosin light chain (alkali)

6

X62654_rna1_at

12.41

7.32

17

ME491 gene extracted from H. sapiens gene for Me491/CD63 antigen

7

M27891_at

12.15

8.83

7

CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)

7

U89922_s_at

12.15

5.24

115

LTB Lymphotoxin-beta

8

X59417_at

12.14

7.99

12

Proteasome iota chain

8

X52056_at

12.14

6.52

37

SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1

9

M19507_at

12.09

7.03

24

MPO Myeloperoxidase

9

M89957_at

12.09

6.92

28

IGB Immunoglobulin-associated beta (B29)

10

M84371_rna1_s_at

11.9

7.18

23

CD19 gene

10

U16954_at

11.9

6.43

40

(AF1q) mRNA

11

M63379_at

11.74

7.56

13

CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)

11

M83667_rna1_s_at

11.74

7.52

14

NF-IL6-beta protein mRNA

12

M16038_at

11.72

7.31

18

LYN V-yes-1 Yamaguchi sarcoma viral related oncogene homolog

12

Y08612_at

11.72

6.31

47

Rabaptin-5 protein

13

D88422_at

11.68

8.72

8

Cystatin A

13

M11722_at

11.68

7.18

21

Terminal transferase mRNA

14

X66401_cds1_at

11.67

5.89

69

LMP2 gene extracted from H. sapiens genes TAP1, TAP2, LMP2, LMP7 and DOB

14

Y00433_at

11.67

4.72

182

GPX1 Glutathione peroxidase 1

15

M63959_at

11.61

6.59

34

LRPAP1 Low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)

15

X51521_at

11.61

6.44

38

VIL2 Villin 2 (ezrin)

16

Z15115_at

11.37

7.49

15

TOP2B Topoisomerase (DNA) II beta (180 kDa)

16

U10868_at

11.37

5.55

92

ALDH7 Aldehyde dehydrogenase 7

17

Y12670_at

11.25

5.67

82

LEPR Leptin receptor

17

U77948_at

11.25

5.6

87

KAI1 Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen detected by monoclonal antibody IA4))

18

U46751_at

11.2

5.8

73

Phosphotyrosine independent ligand p62 for the Lck SH2 domain mRNA

18

L06797_s_at

11.2

5.77

74

Probable G protein-coupled receptor LCR1 homolog

19

M95678_at

11.19

5.73

77

PLCB2 Phospholipase C, beta 2

19

U72936_s_at

11.19

5.38

101

X-linked helicase II

20

S76617_at

11.16

6.43

41

BLK Protein-tyrosine kinase blk

20

L09209_s_at

11.16

5.9

68

APLP2 Amyloid beta (A4) precursor-like protein 2

21

M55150_at

11.11

6.7

32

FAH Fumarylacetoacetate

21

M96803_at

11.11

4.74

180

SPTBN1 Spectrin, beta, non-erythrocytic 1

22

X17042_at

11.08

6.93

27

PRG1 Proteoglycan 1, secretory granule

22

X99920_at

11.08

5.15

124

S100 calcium-binding protein A13

23

S50223_at

10.86

6.65

33

HKR-T1

23

U82759_at

10.86

4.39

229

GB DEF Homeodomain protein HoxA9 mRNA

24

J03589_at

10.83

5.62

85

Ubiquitin-like protein GDX

24

X12447_at

10.83

5.16

122

ALDOA Aldolase A

25

X74262_at

10.8

5.89

70

Retinoblastoma binding protein p48

25

L19437_at

10.8

5.13

127

TALDO Transaldolase

Bø and Jonassen Genome Biology 2002 3:research0017.1   doi:10.1186/gb-2002-3-4-research0017

Open Data