Table 2

The three types of yeast amino-terminal acetyltransferases


NatA
NatB
NatC

Catalytic subunit
Ard1p
Nat3p
Mak3p
Other subunits
Nat1p
Mdm20p
Mak10p

Others
Others
Mak31p
Substrates*
α-Ser-
α-Met-Glu-
α-Met-Ile-

α-Ala-
α-Met-Asp-
α-Met-Leu-

α-Gly-
α-Met-Asn-
α-Met-Trp-

α-Thr-
α-Met-Met-
α-Met-Phe-

*Acetylation occurs on all proteins with α-Met-Glu- and α-Met-Asp-termini but only on subclasses of proteins with the other termini.

Polevoda and Sherman Genome Biology 2002 3:reviews0006.1   doi:10.1186/gb-2002-3-5-reviews0006