Table 2

The three types of yeast amino-terminal acetyltransferases

NatA

NatB

NatC


Catalytic subunit

Ard1p

Nat3p

Mak3p

Other subunits

Nat1p

Mdm20p

Mak10p

Others

Others

Mak31p

Substrates*

α-Ser-

α-Met-Glu-

α-Met-Ile-

α-Ala-

α-Met-Asp-

α-Met-Leu-

α-Gly-

α-Met-Asn-

α-Met-Trp-

α-Thr-

α-Met-Met-

α-Met-Phe-


*Acetylation occurs on all proteins with α-Met-Glu- and α-Met-Asp-termini but only on subclasses of proteins with the other termini.

Polevoda and Sherman Genome Biology 2002 3:reviews0006.1   doi:10.1186/gb-2002-3-5-reviews0006