Genome Biology

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Selection and gene duplication: a view from the genome

Andreas Wagner

Genome Biology 2002, 3:reviews1012-reviews1012.3 doi:10.1186/gb-2002-3-5-reviews1012

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Research article   Open Access

Molecular evolution of the three short PGRPs of the malaria vectors Anopheles gambiae and Anopheles arabiensis in East Africa

Cristina Mendes, Rute Felix, Ana-Margarida Sousa, Joana Lamego, Derek Charlwood, Virgílio E do Rosário, João Pinto, Henrique Silveira BMC Evolutionary Biology 2010, 10:9 (12 January 2010)

Research   Open Access

Coding region structural heterogeneity and turnover of transcription start sites contribute to divergence in expression between duplicate genes

Chungoo Park, Kateryna D Makova Genome Biology 2009, 10:R10 (28 January 2009)

Gene expression data for duplicated gene pairs in humans provides insights into the regulatory factors affecting the expression divergence of these genes and implications for their evolution.

Hypothesis   Open Access

Exon definition as a potential negative force against intron losses in evolution

Deng-Ke Niu Biology Direct 2008, 3:46 (13 November 2008)

If the splicing of pre-mRNAs is initiated by exon definition, an exon larger than a particular size may cause splicing errors . Intron loss that results in oversized exons may thus be deleterious and selected against.

Review   Open Access

From biophysics to evolutionary genetics: statistical aspects of gene regulation

Michael Lässig BMC Bioinformatics 2007, 8(Suppl 6):S7 (27 September 2007)

Research   Open Access Highly Accessed

Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution

Julia Tischler, Ben Lehner, Nansheng Chen, Andrew G Fraser Genome Biology 2006, 7:R69 (2 August 2006)

High-throughput combinatorial RNAi demonstrates that many duplicated genes in C. elegans can retain redundant functions for more than 80 million years