Selection and gene duplication: a view from the genome

doi:10.1186/gb-2002-3-5-reviews1012

Genome Biology

Volume 3
Issue 5

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Selection and gene duplication: a view from the genome

Andreas Wagner

Department of Biology, University of New Mexico, 167A Castetter Hall, Albuquerque, NM 817131-1091, USA

author email corresponding author email

Genome Biology 2002, 3:reviews1012.1-1012.3doi:10.1186/gb-2002-3-5-reviews1012


Published:	15 April 2002

Subject areas: Evolution, Genetics, Bioinformatics

Abstract

Immediately after a gene duplication event, the duplicate genes have redundant functions. Is natural selection therefore completely relaxed after duplication? Does one gene evolve more rapidly than the other? Several recent genome-wide studies have suggested that duplicate genes are always under purifying selection and do not always evolve at the same rate.