Table 4

List of known attenuators in B. subtilis compared with predictions in six other genomes of gram-positive bacteria
B. subtilis
 B. halodurans
 L. innocua
 S. aureus
 C. acetobutylicum
 L. lactis
 S. pneumoniae
ID
 Z-score
 IDa
 No. of predictionsb
 IDa
 No. of predictionsb
 IDa
 No. of predictionsb
 IDa
 No. of predictionsb
 IDa
 No. of predictionsb
 IDa
 No. of predictionsb
 Genec
BS0929
 -8.895
 BH1095
 1
 lin1331
 1
 SAV1302
 0
 -
 -
 L0013
 0
 SP2185
 0
 glycerol-3-phosphate dehydrogenase
(glpD)













BS2825
 -8.473
 BH3061
 1
 lin2091
 0
 SAV2054
 0
 CAC3169
 0
 L0078
 0
 SP0445
 0
 acetolactate synthase (large subunit)
(ilvB)













BS3920
 -6.468
 BH0296
 1
 lin0026
 1
 -
 -
 CAC1407
 1
 L90678
 0
 SP0577
 0
 PTS beta-glucoside-specific enzyme
II ABC component (bglP)
BS2733
 -6.238
 BH1267
 1
 lin1539
 1
 SAV1618
 1
 CAC1678
 1
 L0343
 1
 SP1383
 0
 alanyl-tRNA synthetase (alaS)
BS0013
 -6.126
 BH0024
 1
 lin2890
 1
 SAV0009
 1
 CAC0021
 0
 L150515
 1
 SP0411
 1
 seryl-tRNA synthetase (serS)
BS2749
 -5.839
 BH1251
 2
 lin1555
 1
 SAV1631
 1
 CAC2740
 0
 L0342
 0
 SP2121
 0
 histidyl-tRNA synthetase (hisS)
BS2520
 -5.815
 BH1370
 1
 lin1496
 1
 -
 -
 -
 -
 L101560
 0
 SP1475
 0
 glycyl-tRNA synthetase (alpha
subunit) (glyQ)
BS3396
 -5.767
 -
 -
 -
 -
 -
 -
 -
 -
 L18622
 1
 -
 -
 amino acid permease (yvbW)
BS0215
 -5.526
 -
 -
 -
 -
 SAV0337
 0
 -
 -
 L148346
 0
 -
 -
 glycerol-3-phosphate permease
(glpT)













BS1544
 -5.239
 BH2545
 1
 lin2127
 1
 SAV1193
 1
 CAC3038
 1
 L0350
 1
 SP1659
 1
 isoleucyl-tRNA synthetase (ileS)
BS3798
 -5.164
 BH1856
 0
 -
 -
 -
 -
 CAC0423
 1
 -
 -
 -
 -
 PTS sucrose-specific enzyme II BC
component (sacP)
BS1319
 -5.124
 BH0438
 1
 lin1789
 1
 SAV0356
 0
 -
 -
 L0100
 0
 SP0585
 0
 cobalamin-independent methionine
synthase (metC)
BS3750
 -4.958
 -
 -
 -
 -
 -
 -
 CAC2362
 1
 -
 -
 -
 -
 threonyl-tRNA synthetase (thrZ)
BS3440
 -4.890
 -
 -
 -
 -
 -
 -
 CAC1772
 0
 -
 -
 -
 -
 levansucrase (sacB)
BS2204
 -4.819
 BH1514
 1
 lin1998
 1
 SAV0388
 1
 CAC0873
 0
 L159396
 1
 SP1847
 0
 xanthine phosphoribosyltransferase
(xpt)













BS2139
 -4.756
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 N-acetylmuramoyl-L-alanine amidase
(yomC)













BS2803
 -4.750
 BH3038
 1
 lin1587
 1
 SAV1663
 1
 CAC2399
 2
 L0351
 1
 SP0568
 0
 valyl-tRNA synthetase (valS)
BS0093
 -4.747
 BH0110
 1
 lin0270
 0
 SAV0529
 1
 CAC0687
 1
 L0087
 1
 SP0589
 0
 serine acetyltransferase (cysE)
BS1357
 -4.680
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 hypothetical protein (ykrT)
BS3839
 -4.472
 BH3228
 1
 -
 -
 -
 -
 CAC0780
 1
 -
 -
 -
 -
 tyrosyl-tRNA synthetase (tyrZ)
BS2961
 -4.430
 -
 -
 lin1639
 1
 SAV1729
 1
 CAC0637
 0
 L0359
 0
 SP2100
 0
 tyrosyl-tRNA synthetase (tyrS)
BS1143
 -4.382
 BH2870
 0
 lin2301
 1
 SAV0996
 0
 CAC0626
 1
 L0358
 1
 SP2229
 0
 tryptophanyl-tRNA synthetase (trpS)
BS0254
 -4.309
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 hypothetical protein (yczA)
BS0643
 -4.279
 BH0623
 1
 lin1887
 0
 SAV1064
 0
 CAC1390
 0
 L152487
 0
 SP0053
 0
 phosphoribosylaminoimidazole
carboxylase I (purE)
BS3026
 -4.270
 BH3281
 1
 lin1769
 1
 SAV1760
 0
 CAC0646
 1
 L0352
 0
 SP0254
 0
 leucyl-tRNA synthetase (leuS)
BS2889
 -4.249
 BH3141
 1
 lin1594
 1
 SAV1683
 1
 -
 -
 L0357
 1
 SP1631
 0
 threonyl-tRNA synthetase (thrS)
BS1188
 -4.176
 BH1627
 0
 lin1788
 0
 SAV0359
 2
 -
 -
 L0102
 0
 SP1525
 0
 cystathionine gamma-synthase (yjcI)
BS1313
 -4.086
 BH1505
 1
 -
 -
 -
 -
 -
 -
 L0117
 0
 SP0931
 0
 gamma-glutamyl kinase (proB)
BS3269
 -3.989
 BH3481
 0
 lin2514
 1
 SAV0837
 1
 CAC0984
 1
 L121289
 0
 SP0151
 0
 ABC transporter (ATP-binding
protein) (yusC)
BS3900
 -3.884
 BH3232
 0
 -
 -
 -
 -
 CAC2807
 0
 -
 -
 -
 -
 endo-beta-1,3-1,4 glucanase (bglS)
BS0038
 -3.883
 BH0053
 0
 lin0216
 0
 SAV0490
 0
 CAC2991
 1
 L0353
 0
 SP0788
 0
 methionyl-tRNA synthetase (metS)
BS2858
 -3.784
 BH3111
 1
 lin1184
 0
 SAV1138
 1
 CAC2357
 1
 L0354
 2
 SP0579
 1
 phenylalanyl-tRNA synthethase
(alpha subunit) (pheS)
BS0927
 -3.776
 BH1092
 1
 lin1574
 1
 SAV1300
 1
 CAC1319
 1
 L0015
 0
 SP2184
 0
 glycerol uptake facilitator (glpF)
BS1548
 -3.473
 BH2541
 1
 lin1954
 1
 SAV1198
 1
 CAC2113
 1
 L0227
 1
 SP1278
 1
 uracil phosphoribosyltransferase
(pyrR)













BS3888
 -3.412
 -
 -
 lin0838
 2
 -
 -
 -
 -
 L124252
 0
 -
 -
 hypothetical protein (yxjH)
BS3889
 -3.412
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 hypothetical protein (yxjG)
BS1549
 -3.265
 BH2540
 1
 lin1953
 0
 SAV1199
 2
 CAC2112
 0
 L46118
 0
 SP1286
 0
 uracil permease (pyrP)
BS1550
 -3.120
 BH2539
 1
 lin1952
 0
 SAV1200
 0
 CAC2654
 1
 L45002
 0
 SP1277
 0
 aspartate carbamoyltransferase
(pyrB)













BS1166
 -3.059
 BH2679
 0
 lin0340
 1
 SAV2094
 1
 -
 -
 L0228
 0
 SP0722
 0
 transcriptional regulator (tenA)
BS1360
 -2.966
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 ribulose-bisphosphate carboxylase
(ykrW)













BS1855
 -2.649
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 phosphoglycerate dehydrogenase
(yoaD)













BS2376
 -2.057
 BH1503
 0
 lin0414
 0
 SAV1503
 0
 CAC3252
 0
 L135991
 0
 SP0933
 0
 pyrroline-5-carboxylate reductase
(yqjO)













a "-" signifies that the absence of an ortholog. b "-" signifies that no prediction is made because of absence of ortholog c Gen back annotation of B. subtilis was used for gene definitions and gene names

Lathe et al. Genome Biology 2002 3:preprint0003.1   doi:10.1186/gb-2002-3-6-preprint0003