Genome Biology

official impact factor 6.89

Open Access Highly Access Software

Software and methods for oligonucleotide and cDNA array data analysis

Matthew A Zapala, Daniel J Lockhart, Daniel G Pankratz, Anthony J Garcia, Carrolee Barlow and David J Lockhart*

Author Affiliations

The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA

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Genome Biology 2002, 3:software0001-software0001.9 doi:10.1186/gb-2002-3-6-software0001


Disclaimer: Whilst every effort is made by the authors, editors and publishers to ensure that the software performs as described, they accept no liability whatsoever for the consequences of downloading or using it.

Published: 23 May 2002

Abstract

Two HTML-based programs were developed to analyze and filter gene-expression data: 'Bullfrog' for Affymetrix oligonucleotide arrays and 'Spot' for custom cDNA arrays. The programs provide intuitive data-filtering tools through an easy-to-use interface. A background subtraction and normalization program for cDNA arrays was also built that provides an informative summary report with data-quality assessments. These programs are freeware to aid in the analysis of gene-expression results and facilitate the search for genes responsible for interesting biological processes and phenotypes.