Genome Biology
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MinireviewPrinciples of microbial alchemy: insights from the Streptomyces coelicolor genome sequenceCharles J Thompson  , Doris Fink and Liem D Nguyen Biozentrum, University of Basel, Division of Molecular Microbiology, 70 Klingelbergstrasse, 4056 Basel, Switzerland  author email corresponding author email
Genome Biology 2002,
3:reviews1020.1-1020.4doi:10.1186/gb-2002-3-7-reviews1020
Subject areas: Genome studies, Microbiology and parasitology, Biochemistry and structural biology Abstract
The world's most creative producers of natural pharmaceutical compounds are soil-dwelling bacteria classified as Streptomyces. The availability of the recently completed Streptomyces coelicolor genome sequence provides a link between the folklore of antibiotics and other bioactive compounds to underlying biochemical, molecular genetic and evolutionary principles. | 
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