Genome Biology

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Oxidative stress responses - what have genome-scale studies taught us?

John G Scandalios

Author Affiliations

Department of Genetics, North Carolina State University, Raleigh, NC 27695-7614, USA

Genome Biology 2002, 3:reviews1019-reviews1019.6 doi:10.1186/gb-2002-3-7-reviews1019

Published: 18 June 2002

Abstract

Oxidative stress arises from an imbalance between generation and elimination of reactive oxygen species, often leading to cell death. Genomic tools are expanding our understanding of the antioxidant defenses aerobes have evolved and the recently discovered role(s) of reactive oxygen species in signaling.