Table 1

Preferred and avoided amino acids from proteomes of 10 hyperthermophiles (HT) and thermophiles (T), and 18 mesophiles (M)




HT and T
M





Prokarya
Prokarya
Eukarya


Amino acids
Secondary structures
Polar requirement*
Average (range)
Average (range)

Ratio (HT, T)/M

Gln (Q)
α-helix
8.60
1.88 (1.44-2.08)
4.19(3.25-5.5)
4.28 (3.97-5.24)
0.44
His (H)
α-helix
8.40
1.53 (1.43-1.9)
2.29 (1.83-2.74)
2.4(2.15-2.68)
0.65
Ala (A)
α-helix
7.00
6.38 (5.44-7.84)
9.83 (6-13)
7.64(6.19-11.1)
0.73
Cys (C)
β-strand
4.8
0.81 (0.56-1.27)
1.09 (0.67-1.91)
1.84(1.27-2.21)
0.62
Glu (E)
α-helix
12.50
8.11 (5.53-9.6)
5.8(4.4-7.08)
6.6 (6.39-6.99)
1.34
Lys (K)
α-helix
10.10
7.5 (4.5-10.4)
4.56 (2.61-10)
6.28 (5.6-7.29)
1.49
Tyr (Y)
β-strand
5.40
4.08 (3.2-4.82)
2.74 (1.9-3.48)
3.01 (2.76-3.35)
1.45
Ile (I)
β-strand
4.90
8.42 (7.18-10.5)
5.5(3.28-8.64)
5.46 (4.43-6.51)
1.52

*Taken from 14; Taken from 16; data on HT. T. M in %; only ratios >1.3 and <0.8 are shown.

de Farias and Bonato Genome Biology 2002 3:preprint0006.1   doi:10.1186/gb-2002-3-8-preprint0006