Table 1

Overlapping transcriptional units in mammalian genomes previously described in the literature
Sense	Antisense	References

IGF2R	AIR	[31]
ASE-1	ERCC1	[32]
COPG2	COPG2AS	[33]
MADH5	DAMS	[34]
DLX1	DLX1AS	[35]
DLX6	DLX6AS	[36]
GTROSA26	GTROSA26AS	[37]
IGF2	IGF2AS	[4]
KCNQ1	KCNQ1OT1	[38]
MCM3AP	MCM3APAS	[39]
MSX1	MSX1AS	[11]
KLHL1	SCA8	[12]
GNAS	NESP-AS	[40]
FGF2	NUDT6	[41]
RFPL1	RFPL1S	[42]
RFPL3	RFPL3S	[42]
SLC22A1L	SLC22A1LS	[43]
	ST7OT1
ST7	ST7OT2	[44-46]
	ST7OT3
XIST	TSIX	[9]
MKRN3	ZNF127AS	[47]
HOXA11	HOXA11-AS	[48]
WT1	WIT1	[49]
EIF2S1	Not named	[50]
GNRHR2	RBM8A	[51]
MATN4	RBPSUHL	[52]
PMCH	AROM	[53]
SFRS2	ET	[54]
THRA	NR1D1	[55]
SURF2	SURF4	[56]
TP53	Not named	[57]
MYC	Not named	[58]
MYCN	NCYM	[59]
MBP	MBP	[60,61]
TNFRSF17	Not named	[62]
GNRH1	SH	[63]
HSPA1B	Not named	[64]
PTGER1	PRKCL1	[65]
MYB	Not named	[66]
COL1A1	Not named	[67]
MRPL27	Not named	[68]

We searched reviews [1,2] and carried out keyword searches of PubMed [69], and NCBI LocusLink [70] for pairs of mammalian mRNA species known to share regions of overlap. This list does not include any of the 80 or so recently described examples of overlapping annotated mRNAs [14] ('cis-NATs') that were not observed elsewhere in the literature. A summary of these can be found in the 'cis-NATs' section of the authors' website [71].
Shendure and Church Genome Biology 2002 3:research0044.1 doi:10.1186/gb-2002-3-9-research0044