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A new non-linear normalization method for reducing variability in DNA microarray experiments

Christopher Workman1,2 email, Lars Juhl Jensen2, Hanne Jarmer2, Randy Berka4, Laurent Gautier2, Henrik Bjørn Nielser2, Hans-Henrik Saxild3, Claus Nielsen5, Søren Brunak2 and Steen Knudsen2

1GeneData AG, Maulbeerstrasse 46, CH-4058 Basel, Switzerland

2Center for Biological Sequence Analysis, Technical University of Denmark, DK-2800 Lyngby, Denmark

3Center for Microbiology, Technical University of Denmark, DK-2800 Lyngby, Denmark

4Novozymes Biotechnology, 1445 Drew Avenue, Davis, CA 95616, USA

5Statens Serum Institut, DK-2300 Copenhagen, Denmark

author email corresponding author email

Genome Biology 2002, 3:research0048.1-0048.16doi:10.1186/gb-2002-3-9-research0048

Published: 30 August 2002

Subject areas: Bioinformatics, Genome studies


Additional files

Additional data file 1:

MA plots and signal distributions from all the HIV arrays

Format: TAB Size: 8MB Download file

Additional data file 2:

MA plots and signal distributions from all the glnA arrays

Format: TAB Size: 1.2MB Download file

Additional data file 3:

MA plots and signal distributions from all the tnrA arrays

Format: TAB Size: 1.2MB Download file


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