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Have microarrays failed to deliver for developmental biology?

Rick Livesey

Genome Biology 2002, 3:comment2009-comment2009.5 doi:10.1186/gb-2002-3-9-comment2009

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Exploiting microarrays to reveal differential gene expression in the nervous system

Robert S Griffin, Charles D Mills, Michael Costigan, Clifford J Woolf Genome Biology 2003, 4:105 (29 January 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

What is needed to get the most out of microarrays in terms of accurately and effectively revealing differential gene expression and regulation in the nervous system?

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Impressive expressions: developing a systematic database of gene-expression patterns in Drosophila embryogenesis

Haiqiong Montalta-He, Heinrich Reichert Genome Biology 2003, 4:205 (28 January 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

The establishment of a database of gene-expression patterns derived from systematic highthroughput in situ hybridization studies on whole-mount Drosophila embryos vastly increases the breadth and depth that can be reached by developmental genetics.

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