Genome Biology

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Computational discovery of sense-antisense transcription in the human and mouse genomes

Jay Shendure and George M Church*

Genome Biology 2002, 3:research0044-research0044.14 doi:10.1186/gb-2002-3-9-research0044

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Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling

Rathi D Thiagarajan, Nicole Cloonan, Brooke B Gardiner, Tim R Mercer, Gabriel Kolle, Ehsan Nourbakhsh, Shivangi Wani, Dave Tang, Keerthana Krishnan, Kylie M Georgas, Bree A Rumballe, Han S Chiu, Jason A Steen, John S Mattick, Melissa H Little, Sean M Grimmond BMC Genomics 2011, 12:441 (5 September 2011)

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High-resolution transcription atlas of the mitotic cell cycle in budding yeast

Marina V Granovskaia, Lars J Jensen, Matthew E Ritchie, Joern Toedling, Ye Ning, Peer Bork, Wolfgang Huber, Lars M Steinmetz Genome Biology 2010, 11:R24 (1 March 2010)

A high resolution strand-specific transcriptional atlas of the budding yeast mitotic cell cycle, including both mRNA and non-coding RNA profiles.

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Regulation of MYCN expression in human neuroblastoma cells

Joannes FM Jacobs, Hans van Bokhoven, Frank N van Leeuwen, Christina A Hulsbergen-van de Kaa, I de Vries, Gosse J Adema, Peter M Hoogerbrugge, Arjan PM de Brouwer BMC Cancer 2009, 9:239 (18 July 2009)

Research article   Open Access

Comparative expression profiling in grape (Vitis vinifera) berries derived from frequency analysis of ESTs and MPSS signatures

Alberto Iandolino, Kan Nobuta, Francisco da Silva, Douglas R Cook, Blake C Meyers BMC Plant Biology 2008, 8:53 (12 May 2008)

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Non-random retention of protein-coding overlapping genes in Metazoa

Giulia Soldà, Mikita Suyama, Paride Pelucchi, Silvia Boi, Alessandro Guffanti, Ermanno Rizzi, Peer Bork, Maria Tenchini, Francesca D Ciccarelli BMC Genomics 2008, 9:174 (16 April 2008)

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Overlapping genes in the human and mouse genomes

Chaitanya R Sanna, Wen-Hsiung Li, Liqing Zhang BMC Genomics 2008, 9:169 (14 April 2008)

Research article   Open Access

Uncovering information on expression of natural antisense transcripts in Affymetrix MOE430 datasets

Sebastian Oeder, Joerg Mages, Paul Flicek, Roland Lang BMC Genomics 2007, 8:200 (28 June 2007)

Methodology article   Open Access

Potential pitfalls in the accuracy of analysis of natural sense-antisense RNA pairs by reverse transcription-PCR

Fadia Haddad, Anqi X Qin, Julie M Giger, Hongyan Guo, Kenneth M Baldwin BMC Biotechnology 2007, 7:21 (4 May 2007)

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Prediction of trans-antisense transcripts in Arabidopsis thaliana

Huan Wang, Nam-Hai Chua, Xiu-Jie Wang Genome Biology 2006, 7:R92 (13 October 2006)

A genome-wide screen for trans-natural antisense transcripts in Arabidopsis thaliana suggests that antisense transcripts could be involved in complex regulatory networks in eukaryotes.

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In silico discovery of human natural antisense transcripts

Yuan-Yuan Li, Lei Qin, Zong-Ming Guo, Lei Liu, Hao Xu, Pei Hao, Jiong Su, Yixiang Shi, Wei-Zhong He, Yi-Xue Li BMC Bioinformatics 2006, 7:18 (13 January 2006)

In silico analysis that finds 568 human natural antisense transcripts, of which over 400 have not been reported before, also supports a connection between alternative splicing and antisense-directed regulation.

Research   Open Access

Antisense transcripts with rice full-length cDNAs

Naoki Osato, Hitomi Yamada, Kouji Satoh, Hisako Ooka, Makoto Yamamoto, Kohji Suzuki, Jun Kawai, Piero Carninci, Yasuhiro Ohtomo, Kazuo Murakami, Kenichi Matsubara, Shoshi Kikuchi, Yoshihide Hayashizaki Genome Biology 2003, 5:R5 (11 December 2003)

In this study, 687 sense-antisense transcript pairs from 32,127 full-length rice cDNA sequences were identified by aligning the cDNA sequences with rice genome sequences. The large number of pairs suggests that gene regulation by antisense transcripts occurs in plants and not only in animals.

Methodology article   Open Access Highly Accessed

Expressing functional siRNAs in mammalian cells using convergent transcription

Nham Tran, Murray J Cairns, Ian W Dawes, Greg M Arndt BMC Biotechnology 2003, 3:21 (6 November 2003)

Research article   Open Access

The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12

Alasdair J Edgar BMC Genomics 2003, 4:18 (7 May 2003)

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All that antisense

Jonathan B Weitzman Genome Biology 2003, 4:spotlight-20030319-01 (19 March 2003)

A computational analysis predicts over 1,500 human genes that may be regulated by antisense transcripts.

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Annotation of the Drosophila melanogaster euchromatic genome: a systematic review

Sima Misra, Madeline A Crosby, Christopher J Mungall, Beverley B Matthews, Kathryn S Campbell, Pavel Hradecky, Yanmei Huang, Joshua S Kaminker, Gillian H Millburn, Simon E Prochnik, Christopher D Smith, Jonathan L Tupy, Eleanor J Whitfield, Leyla Bayraktaroglu, Benjamin P Berman, Brian R Bettencourt, Susan E Celniker, Aubrey DNJ de Grey, Rachel A Drysdale, Nomi L Harris, John Richter, Susan Russo, Andrew J Schroeder, ShengQiang Shu, Mark Stapleton, Chihiro Yamada, Michael Ashburner, William M Gelbart, Gerald M Rubin, Suzanna E Lewis Genome Biology 2002, 3:research0083-0083.22 (31 December 2002)

This article is part of a collection on Release 3 of the...

The recent completion of the Drosophila melanogaster genomic sequence to high quality, and the availability of a greatly expanded set of Drosophila cDNA sequences, afforded FlyBase the opportunity to significantly improve genomic annotations.

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A Drosophila full-length cDNA resource

Mark Stapleton, Joe Carlson, Peter Brokstein, Charles Yu, Mark Champe, Reed George, Hannibal Guarin, Brent Kronmiller, Joanne Pacleb, Soo Park, Ken Wan, Gerald M Rubin, Susan E Celniker Genome Biology 2002, 3:research0080-0080.8 (23 December 2002)

This article is part of a collection on Release 3 of the...

High-quality full-insert sequence for 8,921 putative full-length cDNA clones in the Drosophila Gene Collection has been generated and compared to the annotated Release 3 genomic sequence. More than 5,300 cDNAs have been identifieed that contain a complete and accurate protein-coding sequence, corresponding to at least one splice form for 40% of the predicted D. melanogaster genes.