Genome Biology

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Open Access

Hap4p overexpression in glucose-grown Saccharomyces cerevisiae induces cells to enter a novel metabolic state

Romeo Lascaris*, Harmen J Bussemaker, André Boorsma, Matt Piper, Hans van der Spek, Les Grivell and Jolanda Blom

Genome Biology 2002, 4:R3 doi:10.1186/gb-2002-4-1-r3

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Research article   Open Access

Regulation of the yeast metabolic cycle by transcription factors with periodic activities

Aliz R Rao, Matteo Pellegrini BMC Systems Biology 2011, 5:160 (12 October 2011)

Research article   Open Access

Transcriptome analysis of a respiratory Saccharomyces cerevisiae strain suggests the expression of its phenotype is glucose insensitive and predominantly controlled by Hap4, Cat8 and Mig1

Nicklas Bonander, Cecilia Ferndahl, Petter Mostad, Martin DB Wilks, Celia Chang, Louise Showe, Lena Gustafsson, Christer Larsson, Roslyn M Bill BMC Genomics 2008, 9:365 (31 July 2008)

Review   Open Access

Dissecting complex transcriptional responses using pathway-level scores based on prior information

Harmen J Bussemaker, Lucas D Ward, Andre Boorsma BMC Bioinformatics 2007, 8(Suppl 6):S6 (27 September 2007)

Research   Open Access Highly Accessed

Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways

David M Levine, David R Haynor, John C Castle, Sergey B Stepaniants, Matteo Pellegrini, Mao Mao, Jason M Johnson Genome Biology 2006, 7:R93 (17 October 2006)

A comparison of five different measures of pathway expression and a public map of pathway expression in human tissues are presented.

Methodology article   Open Access Highly Accessed

Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computational genomic analysis

Emmitt R Jolly, Chen-Shan Chin, Ira Herskowitz, Hao Li BMC Bioinformatics 2005, 6:275 (18 November 2005)

A new method combining biochemical characterisation with computational genomic analysis has been used successfully to identify targets of the yeast sporulation transcription factor, Ndt80.