The genomics of insecticide resistance
Commonwealth Scientific and Industrial Research Organisation (CSIRO) Entomology, Clunies Ross Street, Black Mountain, ACT 2601, Australia
Genome Biology 2003, 4:202 doi:10.1186/gb-2003-4-1-202Published: 3 January 2003
Genomic technologies are revealing several mechanisms of insecticide resistance involving enhanced detoxification or reduced target-site sensitivity that had previously defied molecular analyses. Genome projects are also revealing some potentially far-reaching consequences for pest-insect genomes of the rapid accumulation of multiple resistance mutations in very short periods of evolutionary time.