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The genomics of insecticide resistance

John G Oakeshott*, Irene Home, Tara D Sutherland and Robyn J Russell

Author Affiliations

Commonwealth Scientific and Industrial Research Organisation (CSIRO) Entomology, Clunies Ross Street, Black Mountain, ACT 2601, Australia

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Genome Biology 2003, 4:202  doi:10.1186/gb-2003-4-1-202

Published: 3 January 2003

Abstract

Genomic technologies are revealing several mechanisms of insecticide resistance involving enhanced detoxification or reduced target-site sensitivity that had previously defied molecular analyses. Genome projects are also revealing some potentially far-reaching consequences for pest-insect genomes of the rapid accumulation of multiple resistance mutations in very short periods of evolutionary time.