MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data
1 Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA
2 Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA
3 Departments of Medicine and Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA
4 Functional Genomics Lab, University of California, Berkeley, CA 94720, USA
Genome Biology 2003, 4:R7 doi:10.1186/gb-2003-4-1-r7Published: 6 January 2003
MAPPFinder is a tool that creates a global gene-expression profile across all areas of biology by integrating the annotations of the Gene Ontology (GO) Project with the free software package GenMAPP http://www.GenMAPP.org webcite. The results are displayed in a searchable browser, allowing the user to rapidly identify GO terms with over-represented numbers of gene-expression changes. Clicking on GO terms generates GenMAPP graphical files where gene relationships can be explored, annotated, and files can be freely exchanged.