Probing the yeast proteome for RNA-processing factors

Sander Granneman¹ and Susan J Baserga¹^,2^,3

¹Departments of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA

²Genetics, Yale University School of Medicine, New Haven, CT 06520, USA

³Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA

author email corresponding author email

Genome Biology 2003, 4:229doi:10.1186/gb-2003-4-10-229


Published:	22 September 2003

Subject areas: Cell biology, Molecular biology, Genome studies, Methods

Abstract

A method has been developed to identify proteins required for the biogenesis of non-coding RNA in yeast, using a microarray to screen for aberrant patterns of RNA processing in mutant strains, and new proteins involved in the processing of ribosomal and non-coding RNAs have been found.