Genome Biology

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A high performance test of differential gene expression for oligonucleotide arrays

William J Lemon, Sandya Liyanarachchi and Ming You*

Genome Biology 2003, 4:R67 doi:10.1186/gb-2003-4-10-r67

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BioMed Central: 9 citations

Method   Open Access Highly Accessed

Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies

Essi Laajala, Tero Aittokallio, Riitta Lahesmaa, Laura L Elo Genome Biology 2009, 10:R77 (16 July 2009)

A novel statistical procedure is presented that uses probe-level information on Affymetrix exon arrays to detect differential splicing.

Methodology article   Open Access Highly Accessed

Determining gene expression on a single pair of microarrays

Robert W Reid, Anthony A Fodor BMC Bioinformatics 2008, 9:489 (21 November 2008)

Methodology article   Open Access Highly Accessed

Empirical Bayes models for multiple probe type microarrays at the probe level

Magnus Åstrand, Petter Mostad, Mats Rudemo BMC Bioinformatics 2008, 9:156 (20 March 2008)

Methodology article   Open Access Highly Accessed

Fisher's combined p-value for detecting differentially expressed genes using Affymetrix expression arrays

Ann Hess, Hari Iyer BMC Genomics 2007, 8:96 (9 April 2007)

Research   Open Access

Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans

Helga David, Gerald Hofmann, Ana Oliveira, Hanne Jarmer, Jens Nielsen Genome Biology 2006, 7:R108 (15 November 2006)

Genome-wide transcription analysis of Aspergillus nidulans grown on different carbon sources and a reconstruction of the complete metabolic network of this filamentous fungi are presented.

Methodology article   Open Access

Correlation test to assess low-level processing of high-density oligonucleotide microarray data

Alexander Ploner, Lance D Miller, Per Hall, Jonas Bergh, Yudi Pawitan BMC Bioinformatics 2005, 6:80 (31 March 2005)

A new graphical method for assessing the quality of low-level analysis of microarray expression data shows, among other things, that normalization, while necessary, should not be based on housekeeping genes.

Method   Open Access

Genomic analysis of early murine mammary gland development using novel probe-level algorithms

Stephen R Master, Alexander J Stoddard, L Charles Bailey, Tien-Chi Pan, Katherine D Dugan, Lewis A Chodosh Genome Biology 2005, 6:R20 (1 February 2005)

A novel algorithm (ChipStat) is presented for detecting gene-expression changes from Affymetrix microarray data. The method is used to identify changes in murine mammary development.

Research   Open Access Highly Accessed

Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

Sung E Choe, Michael Boutros, Alan M Michelson, George M Church, Marc S Halfon Genome Biology 2005, 6:R16 (28 January 2005)

A 'spike-in' experiment for Affymetrix GeneChips is described that provides a defined dataset of 3,860 RNA species. A 'best route' combination of analysis methods is presented which allows detection of approximately 70% of true positives before reaching a 10% false discovery rate.

Research article   Open Access

Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide arrays

Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizabeth Winzeler, Yingyao Zhou BMC Bioinformatics 2004, 5:42 (20 April 2004)