Genome Biology

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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

Karen I Zeller, Anil G Jegga, Bruce J Aronow, Kathryn A O'Donnell and Chi V Dang*

Genome Biology 2003, 4:R69 doi:10.1186/gb-2003-4-10-r69

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BioMed Central: 12 citations

Research article   Open Access

Deciphering c-MYC-regulated genes in two distinct tissues

Samuel C Robson, Lesley Ward, Helen Brown, Heather Turner, Ewan Hunter, Stella Pelengaris, Michael Khan BMC Genomics 2011, 12:476 (30 September 2011)

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Key signalling nodes in mammary gland development and cancer: Myc

Nancy E Hynes, Tina Stoelzle Breast Cancer Research 2009, 11:210 (15 October 2009)

This article is part of a collection on Key signalling nodes in...

Research article   Open Access

c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland

Tina Stoelzle, Patrick Schwarb, Andreas Trumpp, Nancy E Hynes BMC Biology 2009, 7:63 (28 September 2009)

c-myc knockout mice have slower alveolar cell proliferation in the mammary gland during pregnancy and less efficient translation of mRNAs involved in milk production, showing c-Myc to be important for pregnancy and lactation in mice.

Research article   Open Access

A Myc-regulated transcriptional network controls B-cell fate in response to BCR triggering

Jernej Murn, Irena Mlinaric-Rascan, Pierre Vaigot, Olivier Alibert, Vincent Frouin, Xavier Gidrol BMC Genomics 2009, 10:323 (17 July 2009)

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Novel sequential ChIP and simplified basic ChIP protocols for promoter co-occupancy and target gene identification in human embryonic stem cells

Ricardo B Medeiros, Kate J Papenfuss, Brian Hoium, Kristen Coley, Joy Jadrich, Saik-Kia Goh, Anuratha Elayaperumal, Julio E Herrera, Ernesto Resnik, Hsiao-Tzu Ni BMC Biotechnology 2009, 9:59 (29 June 2009)

A novel, fast, sequential chromatin immunoprecipitation (ChIP) protocol with high sensitivity identified promoter co-occupancy for transcription factors in human embryonic stem cells, providing a useful high-throughput tool to investigate protein–DNA interactions.

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Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual information

Weijun Luo, Kurt D Hankenson, Peter J Woolf BMC Bioinformatics 2008, 9:467 (3 November 2008)

Research   Open Access

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

Frank Westermann, Daniel Muth, Axel Benner, Tobias Bauer, Kai-Oliver Henrich, André Oberthuer, Benedikt Brors, Tim Beissbarth, Jo Vandesompele, Filip Pattyn, Barbara Hero, Rainer König, Matthias Fischer, Manfred Schwab Genome Biology 2008, 9:R150 (13 October 2008)

Differences in MYCN/c-MYC target gene expression are associated with distinct neuroblastoma subtypes and clinical outcome.

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Transcription profiling of lung adenocarcinomas of c-myc-transgenic mice: Identification of the c-myc regulatory gene network

Susanne Reymann, Jürgen Borlak BMC Systems Biology 2008, 2:46 (22 May 2008)

Research   Open Access

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

Scott H Robbins, Thierry Walzer, Doulaye Dembélé, Christelle Thibault, Axel Defays, Gilles Bessou, Huichun Xu, Eric Vivier, MacLean Sellars, Philippe Pierre, Franck R Sharp, Susan Chan, Philippe Kastner, Marc Dalod Genome Biology 2008, 9:R17 (24 January 2008)

Genome-wide expression profiling of mouse and human leukocytes reveal conserved transcriptional programs of plasmacytoid or conventional dendritic cell subsets.

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Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility

Xavier Solé, Pilar Hernández, Miguel de Heredia, Lluís Armengol, Benjamín Rodríguez-Santiago, Laia Gómez, Christopher A Maxwell, Fernando Aguiló, Enric Condom, Jesús Abril, Luis Pérez-Jurado, Xavier Estivill, Virginia Nunes, Gabriel Capellá, Stephen B Gruber, Víctor Moreno, Miguel Pujana BMC Genomics 2008, 9:12 (11 January 2008)

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Genome position and gene amplification

Pavla Gajduskova, Antoine M Snijders, Serena Kwek, Ritu Roydasgupta, Jane Fridlyand, Taku Tokuyasu, Daniel Pinkel, Donna G Albertson Genome Biology 2007, 8:R120 (21 June 2007)

Genomic analyses of human cells expressing dihydrofolate reductase provide insight into the effects of genome position on the propensity for a drug-resistance gene to amplify in human cells.

Research article   Open Access

Stimulation of Myc transactivation by the TATA binding protein in promoter-reporter assays

John F Barrett, Linda A Lee, Chi V Dang BMC Biochemistry 2005, 6:7 (5 May 2005)

Although transcriptional transactivation by the c-Myc oncoprotein in reporter assays is generally weak, addition of the TATA-binding protein TBP strongly stimulates this activity and might therefore help in the hunt for Myc target genes.