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Multi-level response of the yeast genome to glucose

Ruud Geladé, Sam Van de Velde, Patrick Van Dijck and Johan M Thevelein*

Author Affiliations

Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, Katholieke Universiteit Leuven and Department of Molecular Microbiology, Flemish Interuniversity Institute of Biotechnology (V.I.B.), Kasteelpark Arenberg 31, 6-3001 Leuven-Heverlee, Flanders, Belgium

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Genome Biology 2003, 4:233  doi:10.1186/gb-2003-4-11-233

Published: 15 October 2003

Abstract

The yeast Saccharomyces cerevisiae shows a great variety of cellular responses to glucose via several glucose-sensing and signaling pathways. Recent microarray analysis has revealed multiple levels of genomic sensitivity to glucose and highlighted the power of genome-wide analysis to detect cellular responses to minute environmental changes.