Detergent-resistant membranes and the protein composition of lipid rafts

doi:10.1186/gb-2003-4-11-234

Genome Biology

Volume 4
Issue 11

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Detergent-resistant membranes and the protein composition of lipid rafts

Anthony I Magee and Ingela Parmryd

Division of Biomedical Sciences, Imperial College Faculty of Medicine, SAF Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

author email corresponding author email

Genome Biology 2003, 4:234doi:10.1186/gb-2003-4-11-234


Published:	27 October 2003

Subject areas: Cell biology, Biochemistry and structural biology, Genome studies

Abstract

The plasma membrane of eukaryotic cells contains lipid rafts with protein and lipid compositions differing from the bulk plasma membrane. Several recent proteomic studies have addressed the composition of lipid rafts, but the different definitions used for lipid rafts need scrutinizing before results can be evaluated.