Extending knowledge of Escherichia coli metabolism by modeling and experiment

doi:10.1186/gb-2003-4-11-235

Genome Biology
Volume 4
Issue 11

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Extending knowledge of Escherichia coli metabolism by modeling and experiment

Eberhard O Voit¹ and Monica Riley²

¹Medical University of South Carolina, Charleston, SC 29425, USA

²Marine Biological Laboratory, Woods Hole, MA 02543, USA

author email corresponding author email

Genome Biology 2003, 4:235doi:10.1186/gb-2003-4-11-235


Published:	28 October 2003

Subject areas: Microbiology and parasitology, Genome studies, Biochemistry and structural biology, Methods, Model organisms

Abstract

One of the challenges for 'post-genomic' biology is the integration of data from many different sources. Two recent studies independently take steps towards this goal for Escherichia coli, using mathematical modeling and a combination of gene expression and protein levels to predict new gene functions and metabolic behaviors.