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Resolution: standard / high Figure 2.
Comparison of linear ICA (NMLE), nonlinear ICA with Gaussian RBF kernel (NICAgauss),
and PCA, on the yeast cell cycle spotted array data (dataset 1). For each functional
category within GO and KEGG, the value of -log10 (p value) with the smallest p value from one method is plotted against the corresponding value from the other method.
(a) Gene clusters based on the linear ICA components are compared with those based on
PCA when C for PCA is fixed to its optimal value 37.5. (b) Gene clusters based on the linear ICA components are compared with those based on
PCA with different values of C. (c) Gene clusters based on the nonlinear ICA components are compared with those based
on linear ICA. (d) Gene clusters based on the nonlinear ICA components are compared with those based
on PCA. Overall, nonlinear ICA performed slightly better than NMLE, and both methods
performed significantly better than PCA.
Lee and Batzoglou Genome Biology 2003 4:R76 doi:10.1186/gb-2003-4-11-r76 |