Genome Biology

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Localizing the proteome

Jeremy C Simpson and Rainer Pepperkok*

Genome Biology 2003, 4:240 doi:10.1186/gb-2003-4-12-240

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BioMed Central: 4 citations

Methodology article   Open Access

Dual channel rank-based intensity weighting for quantitative co-localization of microscopy images

Vasanth R Singan, Thouis R Jones, Kathleen M Curran, Jeremy C Simpson BMC Bioinformatics 2011, 12:407 (21 October 2011)

Research   Open Access Highly Accessed

Towards defining the nuclear proteome

J Lynn Fink, Seetha Karunaratne, Amit Mittal, Donald M Gardiner, Nicholas Hamilton, Donna Mahony, Chikatoshi Kai, Harukazu Suzuki, Yosihide Hayashizaki, Rohan D Teasdale Genome Biology 2008, 9:R15 (23 January 2008)

Direct evidence is reported for 2,568 mammalian proteins within the nuclear proteome, consisting of at least 14% of the entire proteome.

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The subcellular localization of the mammalian proteome comes a fraction closer

Jeremy C Simpson, Rainer Pepperkok Genome Biology 2006, 7:222 (23 June 2006)

A recent study shows the successful application of protein correlation profiling to the subcellular localization of organelle proteins in mammalian cells.

Methodology article   Open Access

Improved tagging strategy for protein identification in mammalian cells

Agnieszka Bialkowska, Xian-Yang Zhang, Jakob Reiser BMC Genomics 2005, 6:113 (4 September 2005)

Full-length endogenous proteins can be expressed as green fluorescent fusion proteins from their own promoters using a lentivirus vector that displays several improvements over its retrovirus predecessors.