Genome Biology

official impact factor 6.89

Myriads of protein families, and still counting

Victor Kunin, Ildefonso Cases, Anton J Enright, Victor de Lorenzo and Christos A Ouzounis*

Genome Biology 2003, 4:401 doi:10.1186/gb-2003-4-2-401

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Research   Open Access Highly Accessed

The global landscape of sequence diversity

José Peregrín-Álvarez, John Parkinson Genome Biology 2007, 8:R238 (8 November 2007)

Comparison of genomic and EST sequences reveals a greater genetic diversity within eukaryotes than prokaryotes and enables identification of taxon-specific sequences.

Research article   Open Access

A functional hierarchical organization of the protein sequence space

Noam Kaplan, Moriah Friedlich, Menachem Fromer, Michal Linial BMC Bioinformatics 2004, 5:196 (14 December 2004)

Opinion   Free

Progress towards mapping the universe of protein folds

Alastair Grant, David Lee, Christine Orengo Genome Biology 2004, 5:107 (29 April 2004)

How well can the current set of known protein families and folds be used to estimate the total number of folds in nature, and will structural genomics initiatives yield representatives for all the major protein families within a reasonable time scale?