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Correspondence

Myriads of protein families, and still counting

Victor Kunin1, Ildefonso Cases1, Anton J Enright1, Victor de Lorenzo12 and Christos A Ouzounis1*

Author Affiliations

1 Addresses: Computational Genomics Group, The European Bioinformatics Institute, EMBL Cambridge Outstation, Cambridge CB10 1SD, UK

2 Centro Nacional de BiotecnologĂ­a CSIC, Campus de Cantoblanco 28049 Madrid, Spain

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Genome Biology 2003, 4:401  doi:10.1186/gb-2003-4-2-401

Published: 28 January 2003

Abstract

From the historical record of genome sequencing, we show that the rate of discovery of new families has remained constant over time, indicating that our knowledge of sequence space is far from complete.