Table 1 |
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|
PdL lines |
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| Life-span phenotype* |
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|
|
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| Line name |
Gene (enzyme) |
-DOX |
+DOX |
% Change (p) |
Date of assay |
|
|
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| PdL lines crossed to rtTA(3)E2 |
|||||
| PdL(3)3E36 |
Red herring/encore |
60.42 ± 0.920 |
64.34 ± 0.864 |
+6.50 (0.0021) |
7 October 1999 |
| 55.20 ± 0.729 |
64.55 ± 0.757 |
+16.95 (<0.0001) |
6 July 1999 |
||
| 66.91 ± 0.980 |
75.59 ± 0.910 |
+13.00 (<0.0001) |
14 February 2001 |
||
| 56.56 ± 0.709 |
62.44 ± 0.854 |
+10.38 (<0.0001) |
7 August 2001 |
||
| PdL(2)4G14 |
VhaSFD |
76.05 ± 1.039 |
82.71 ± 1.088 |
+8.75 (<0.0001) |
14 November 2000 |
| 69.28 ± 1.077 |
76.24 ± 1.538 |
+10.6 (0.0002) |
18 July 2000 |
||
| 73.79 ± 1.410 |
77.67 ± 1.251 |
+5.27 (0.0404) |
6 March 2001 |
||
| 55.40 ± 0.810 |
59.34 ± 0.887 |
+7.11 (0.0011) |
21 August 2001 |
||
| PdL(3)2C33 |
Sugar baby CG7334 |
73.91 ± 1.501 |
80.32 ± 1.392 |
+8.67 (0.0019) |
15 November 2000 |
| 71.75 ± 1.105 |
77.74 ± 1.169 |
+8.35 (0.0002) |
3 July 2000 |
||
| 68.99 ± 1.100 |
72.22 ± 1.034 |
+4.68 (0.0329) |
6 March 2001 |
||
| 56.77 ± 0.950 |
57.68 ± 0.617 |
+1.59 (0.4241) |
7 August 2001 |
||
| Oregon-R |
62.70 ± 0.963 |
63.81 ± 1.299 |
+1.76 (0.4954) |
12 August 2001 |
|
| Oregon-R |
68.20 ± 0.978 |
71.41 ± 1.255 |
+4.71 (0.0438) |
28 September 2000 |
|
| Oregon-R |
71.27 ± 1.407 |
72.46 ± 1.247 |
+1.66 (0.5278) |
11 July 2000 |
|
| Oregon-R |
76.14 ± 1.498 |
74.45 ± 1.492 |
-2.23 (0.4236) |
16 May 2000 |
|
| Oregon-R |
68.84 ± 0.903 |
65.30 ± 1.175 |
-5.14 (0.0176) |
7 October 1999 |
|
| PdL lines crossed to rtTA(3)M1 |
|||||
| PdL(3)8S64 |
filamin |
58.87 ± 1.295 |
64.11 ± 1.066 |
+8.76 (0.0020) |
13 December 2000 |
| 56.00 ± 1.202 |
60.68 ± 1.103 |
+8.37 (0.0044) |
3 May 2001 |
||
| PdL(3)8S25 |
fwd |
58.90 ± 0.868 |
62.99 ± 0.912 |
+6.93 (0.0013) |
22 December 2000 |
| (1-phosphatidylinositol 4-kinase) |
56.25 ± 0.940 |
61.31 ± 1.028 |
+9.00 (0.0003) |
3 May 2001 |
|
| PdL(3)8R128 |
Cct1 |
59.68 ± 1.192 |
64.34 ± 1.052 |
+7.80 (0.0035) |
27 February 2001 |
| (cholinephosphate cytidylyltransferase) |
56.54 ± 0.789 |
59.85 ± 0.852 |
+5.93 (0.0041) |
10 July 2001 |
|
| Oregon-R |
60.44 ± 1.296 |
61.61 ± 1.350 |
-1.96 (0.5337) |
13 July 2001 |
|
| Oregon-R |
65.79 ± 1.009 |
68.68 ± 0.819 |
+4.39 (0.0266) |
2 May 2001 |
|
| Oregon-R |
65.45 ± 1.304 |
66.93 ± 1.091 |
+2.20 (0.3824) |
30 November 2000 |
|
|
|
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|
*Mean life span ± SEM, p-value for unpaired, two-sided t-test in parentheses. |
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|
Landis et al. Genome Biology 2003 4:R8 doi:10.1186/gb-2003-4-2-r8 |
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