Genome Biology

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Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray

Zbynek Bozdech, Jingchun Zhu, Marcin P Joachimiak, Fred E Cohen, Brian Pulliam and Joseph L DeRisi*

Genome Biology 2003, 4:R9 doi:10.1186/gb-2003-4-2-r9

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BioMed Central: 29 citations

Research article   Open Access

Protease-associated cellular networks in malaria parasite Plasmodium falciparum

Timothy G Lilburn, Hong Cai, Zhan Zhou, Yufeng Wang BMC Genomics 2011, 12(Suppl 5):S9 (23 December 2011)

Research article   Open Access

Array CGH Phylogeny: How accurate are Comparative Genomic Hybridization-based trees?

Luz B Gilbert, Takao Kasuga, N Louise Glass, John W Taylor BMC Genomics 2011, 12:487 (6 October 2011)

Research   Open Access Highly Accessed

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

Antoine Claessens, Ashfaq Ghumra, Archna P Gupta, Sachel Mok, Zbynek Bozdech, J Alexandra Rowe Malaria Journal 2011, 10:180 (30 June 2011)

The authors have extended a MicroArray resource by adding members of different variant surface antigen (VSA) gene families and then using this new chip to identify the genes involved with a specific adherence phenotype (rosetting). This confirms that cytoadherence studies have been right to concentrate on PfEMP1.

Proceedings   Open Access

UPS 2.0: unique probe selector for probe design and oligonucleotide microarrays at the pangenomic/ genomic level

Shu-Hwa Chen, Chen-Zen Lo, Sheng-Yao Su, Bao-Han Kuo, Chao A Hsiung, Chung-Yen Lin BMC Genomics 2010, 11(Suppl 4):S6 (2 December 2010)

Research article   Open Access

VIPR: A probabilistic algorithm for analysis of microbial detection microarrays

Adam F Allred, Guang Wu, Tuya Wulan, Kael F Fischer, Michael R Holbrook, Robert B Tesh, David Wang BMC Bioinformatics 2010, 11:384 (20 July 2010)

Research article   Open Access Highly Accessed

Defining species specific genome differences in malaria parasites

Kingsley JL Liew, Guangan Hu, Zbynek Bozdech, Preiser R Peter BMC Genomics 2010, 11:128 (23 February 2010)

Research article   Open Access

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei

Sarah Kabani, Katelyn Fenn, Alan Ross, Al Ivens, Terry K Smith, Peter Ghazal, Keith Matthews BMC Genomics 2009, 10:427 (11 September 2009)

Research article   Open Access

Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3

Ben-Wen Li, Amy C Rush, Makedonka Mitreva, Yong Yin, David Spiro, Elodie Ghedin, Gary J Weil BMC Genomics 2009, 10:267 (15 June 2009)

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Reality check for malaria proteomics

Robert E Sinden Genome Biology 2009, 10:211 (26 February 2009)

Post-translationally modified protein isoforms are common in red blood cell stages of the malaria parasite.

Methodology article   Open Access

Mismatch oligonucleotides in human and yeast: guidelines for probe design on tiling microarrays

Michael Seringhaus, Joel Rozowsky, Thomas Royce, Ugrappa Nagalakshmi, Justin Jee, Michael Snyder, Mark Gerstein BMC Genomics 2008, 9:635 (31 December 2008)

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Comparative genomic analysis of Mycobacterium avium subspecies obtained from multiple host species

Michael L Paustian, Xiaochun Zhu, Srinand Sreevatsan, Suelee Robbe-Austerman, Vivek Kapur, John P Bannantine BMC Genomics 2008, 9:135 (20 March 2008)

Proceedings   Open Access

The unique probe selector: a comprehensive web service for probe design and oligonucleotide arrays

Shu-Hwa Chen, Chen-Zen Lo, Ming-Chi Tsai, Chao A Hsiung, Chung-Yen Lin BMC Bioinformatics 2008, 9(Suppl 1):S8 (13 February 2008)

Research article   Open Access

Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL3B

Jennifer M Reynolds, Kamal El Bissati, Jens Brandenburg, Arthur Günzl, Choukri Mamoun BMC Clinical Pharmacology 2007, 7:13 (23 October 2007)

Methodology article   Open Access

Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy

Guangan Hu, Manuel Llinás, Jingguang Li, Peter Preiser, Zbynek Bozdech BMC Bioinformatics 2007, 8:350 (19 September 2007)

Research   Open Access Highly Accessed

Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle

Jennifer L Shock, Kael F Fischer, Joseph L DeRisi Genome Biology 2007, 8:R134 (7 August 2007)

A consistent bias in tree reconciliation methods is described that occurs when the inferred gene tree is not correct, casting doubt on previous conclusions about ancient duplications and losses in vertebrate genome history.

Research article   Open Access

Construction and validation of a first-generation Bordetella bronchiseptica long-oligonucleotide microarray by transcriptional profiling the Bvg regulon

Tracy L Nicholson BMC Genomics 2007, 8:220 (6 July 2007)

Research article   Open Access Highly Accessed

Identification of putative cis-regulatory elements in Cryptosporidium parvum by de novo pattern finding

Nandita Mullapudi, Cheryl A Lancto, Mitchell S Abrahamsen, Jessica C Kissinger BMC Genomics 2007, 8:13 (9 January 2007)

In the intracellular parasite Cryptosporidium parvum, an AIDS-related pathogen, functionally related genes are co-expressed during the life cycle of the parasite and appear to be co-regulated by conserved upstream motifs.

Software   Open Access

PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens

Sreedevi Thiyagarajan, Miloslav Karhanek, Michael Akhras, Ronald W Davis, Nader Pourmand BMC Bioinformatics 2006, 7:500 (14 November 2006)

Method   Open Access Highly Accessed

Zebrafish promoter microarrays identify actively transcribed embryonic genes

Fiona C Wardle, Duncan T Odom, George W Bell, Bingbing Yuan, Timothy W Danford, Elizabeth L Wiellette, Elizabeth Herbolsheimer, Hazel L Sive, Richard A Young, James C Smith Genome Biology 2006, 7:R71 (4 August 2006)

The development and verification of a genomic microarray for ChIP-chip analysis of zebrafish genes is described.

Research   Open Access

Transcriptome analysis of antigenic variation in Plasmodium falciparum - var silencing is not dependent on antisense RNA

Stuart A Ralph, Emmanuel Bischoff, Denise Mattei, Odile Sismeiro, Marie-Agnès Dillies, Ghislaine Guigon, Jean-Yves Coppee, Peter H David, Artur Scherf Genome Biology 2005, 6:R93 (31 October 2005)

A microarray analysis of Plasmodium falciparum selected to express different var genes suggests that antisense transcripts are not responsible for the transcriptional silencing of non-expressed var genes.

Method   Open Access

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns

Anatoly Urisman, Kael F Fischer, Charles Y Chiu, Amy L Kistler, Shoshannah Beck, David Wang, Joseph L DeRisi Genome Biology 2005, 6:R78 (30 August 2005)

An algorithm, E-Predict, for microarray-based species identification is presented. E-Predict compares an observed hybridization pattern with a set of theoretical energy profiles. Each profile represents a species that may be identified.

Method   Open Access

Transcript copy number estimation using a mouse whole-genome oligonucleotide microarray

Mark G Carter, Alexei A Sharov, Vincent VanBuren, Dawood B Dudekula, Condie E Carmack, Charlie Nelson, Minoru SH Ko Genome Biology 2005, 6:R61 (30 June 2005)

An in-situ-synthesized 60-mer oligonucleotide microarray designed to detect transcripts from all mouse genes is presented. Exogenous RNA controls derived from yeast allow quantitative estimation of absolute endogenous transcript abundance

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A generic approach for the design of whole-genome oligoarrays, validated for genomotyping, deletion mapping and gene expression analysis on Staphylococcus aureus

Yvan Charbonnier, Brian Gettler, Patrice François, Manuela Bento, Adriana Renzoni, Pierre Vaudaux, Werner Schlegel, Jacques Schrenzel BMC Genomics 2005, 6:95 (17 June 2005)

Research   Open Access Highly Accessed

Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes

Zbynek Bozdech, Hagai Ginsburg Malaria Journal 2005, 4:17 (18 March 2005)

In order to be useful, the huge amount of transcriptomic data now available for malarial parasites needs to be linked to already available biochemical and functional data. This was done here for the pentose phosphate pathway of carbohydrate metabolism.

Research article   Open Access

Secondary structure in the target as a confounding factor in synthetic oligomer microarray design

Vladyslava G Ratushna, Jennifer W Weller, Cynthia J Gibas BMC Genomics 2005, 6:31 (8 March 2005)

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Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote

Pauline Ward, Leila Equinet, Jeremy Packer, Christian Doerig BMC Genomics 2004, 5:79 (12 October 2004)

The common and divergent protein kinase sequences in the genome of the malaria parasite Plasmodium falciparum have been identified and classified.

Methodology   Open Access

In vivo transcriptional profiling of Plasmodium falciparum

Johanna P Daily, Karine G Le Roch, Ousmane Sarr, Xuemin Fang, Yingyao Zhou, Omar Ndir, Soulyemane Mboup, Ali Sultan, Elizabeth A Winzeler, Dyann F Wirth Malaria Journal 2004, 3:30 (5 August 2004)

This methodology paper reports the first attempt to use samples of parasites taken directly from the patient to explore the malarial transcriptome.

Research   Open Access Highly Accessed

Antioxidant defense in Plasmodium falciparum – data mining of the transcriptome

Zbynek Bozdech, Hagai Ginsburg Malaria Journal 2004, 3:23 (9 July 2004)

Mining the genome of the malaria parasite in terms of the relative transcription of the various genes of a given biochemical pathway at different stages of the erythrocytic cycle, enables the authors to link the transcriptome data with what is already known of the antioxydant machinery of the parasite. A first step in establishing a gene-function relationship.

Research   Open Access

Integrative analysis of intraerythrocytic differentially expressed transcripts yields novel insights into the biology of Plasmodium falciparum

Raphael D Isokpehi, Winston A Hide Malaria Journal 2003, 2:38 (14 November 2003)

A useful attempt to integrate information from genomic sequencing, micro-array data and published proteomic data mostly from Plasmodium falciparum.