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Paper report

Articles selected by Faculty of 1000: p53 gene silencing; duplications in the Arabidopsis genome; RNA interference and disease protection; arraying environmental gene diversity; predicting RNA folding patterns.

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Genome Biology 2003, 4:312  doi:10.1186/gb-2003-4-3-312

The electronic version of this article is the complete one and can be found online at: http://genomebiology.com/2003/4/3/312/


Published:26 February 2003

© 2003 BioMed Central Ltd

p53 gene silencing

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Hemann MT, Fridman JS, Zilfou JT, Hernando E, Paddison PJ, Cordon-Cardo C, Hannon GJ, Lowe SW. Nat Genet 2003, doi:10.1038/ng1091

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Hemann webcite

Duplications in the Arabidopsis genome

A recent polyploidy superimposed on older large-scale duplications in the Arabidopsis genome. Blanc G, Hokamp K, Wolfe KH. Genome Res 2003, 13:137-144.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Blanc webcite

RNA interference and disease protection

RNA interference targeting Fas protects mice from fulminant hepatitis. Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman J. Nat Med 2003, doi:10.1038/nm828

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Song webcite

Arraying environmental gene diversity

Oligonucleotide microarray for the study of functional gene diversity in the nitrogen cycle in the environment. Taroncher-Oldenburg G, Griner EM, Francis CA, Ward BB. Appl Environ Microbiol 2003, 69:1159-1171.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Taroncher webcite

Predicting RNA folding patterns

Discovering well-ordered folding patterns in nucleotide sequences. Le SY, Chen JH, Konings D, Maizel JV. Bioinformatics 2003 19:354-361.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Le webcite

Genome Biologypaper reports
Genome Biology aims to highlight significant research articles newly published in other journals. From 2003, individual paper reports have been replaced by summaries of articles of interest to Genome Biology readers, taken from those highlighted by Faculty of 1000, a new online literature awareness tool published by BioMed Central. Faculty of 1000 systematically and comprehensively reviews the most interesting recent articles published in the biological sciences on the basis of recommendations of a faculty of over 1,400 selected leading researchers.