p53 gene silencing
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Hemann MT, Fridman JS, Zilfou JT, Hernando E, Paddison PJ, Cordon-Cardo C, Hannon GJ, Lowe SW. Nat Genet 2003, doi:10.1038/ng1091
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Hemann webcite
Duplications in the Arabidopsis genome
A recent polyploidy superimposed on older large-scale duplications in the Arabidopsis genome. Blanc G, Hokamp K, Wolfe KH. Genome Res 2003, 13:137-144.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Blanc webcite
RNA interference and disease protection
RNA interference targeting Fas protects mice from fulminant hepatitis. Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman J. Nat Med 2003, doi:10.1038/nm828
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Song webcite
Arraying environmental gene diversity
Oligonucleotide microarray for the study of functional gene diversity in the nitrogen cycle in the environment. Taroncher-Oldenburg G, Griner EM, Francis CA, Ward BB. Appl Environ Microbiol 2003, 69:1159-1171.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Taroncher webcite
Predicting RNA folding patterns
Discovering well-ordered folding patterns in nucleotide sequences. Le SY, Chen JH, Konings D, Maizel JV. Bioinformatics 2003 19:354-361.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Le webcite
