Table 4

Comparison of the present stress-inducible cDNA collection with stress/defense genes identified in other large-scale studies

Study

Cut-off

Induced/repressed clones

MIPS id

Represented in stress cDNA collection

Treatment

[7]

2.5-fold

413

308

50 (16%)

Benzothiadiazol treatment, bacterial and oomycete pathogen

[17]

2.5-fold

705

507

160 (32%)

Fungal pathogen, SA, MJ, ethylene

[48]

2-fold

657

281

73 (26%)

Mechanical wounding

[18]

1.5-fold

175

114

32 (28%)

Hydrogen peroxide

[49]

1.5-fold

75

69

16 (23%)

Heat treatment and senescence

Maleck et al. [7] studied 10,000 EST clones obtained from the Arabidopsis Biological Resource Center representing approximately 7,000 genes. Schenk et al. [17] studied a custom array containing 2,375 ESTs with a biased representation of putative defense-associated and regulatory genes. From our estimate of redundancy (approximately 30%), this array contains 1,662 distinct genes. The study of Cheong et al. [48] involved the Affymetrix Arabidopsis Genome GeneChip array representing 8,200 genes. Desikan et al. [18] studied Arabidopsis Functional Genomics Consortium microarrays containing 11,000 EST clones representing approximately 7,800 distinct genes. The custom array of Swidzinski et al. [49] contained 75 ESTs previously implicated in programmed cell-death responses such as senescence and hypersensitive response.

Mahalingam et al. Genome Biology 2003 4:R20   doi:10.1186/gb-2003-4-3-r20