Figure 6.

Expression of TCL (tumor-classifier) genes was correlated with the malignant potential of colorectal cancer. Results used the 100 cancer and 11 normal tissues. (a) Correlation with distant metastasis. We aligned the 12 genes listed at the top of Table 1 from left to right horizontally. All samples were then sorted vertically by the average of the gene-expression levels of the 12 genes. The border of groups 1 and 2 is set at 0. The right bar indicates remote metastasis status, with red, green and blue representing remote metastasis positive, remote metastasis negative, and normal tissues, respectively. (b) Kaplan-Meier plot analysis of groups 1 and 2. Vertical axis, fraction of survival; horizontal axis, survival time in years. The groups of patients analyzed consisted of either all stages (left) or Dukes' B and C stages only (right). All the expression data and relevant clinical information are available as additional data files.