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ProSplicer: a database of putative alternative splicing information derived from protein, mRNA and expressed sequence tag sequence data

Hsien-Da Huang1, Jorng-Tzong Horng1,2*, Chau-Chin Lee3 and Baw-Jhiune Liu3

Author Affiliations

1 Department of Computer Science and Information Engineering, National Central University, Jung-Li City 320, Taiwan

2 Department of Life Science, National Central University, Jung-Li City 320, Taiwan

3 Department of Computer Science and Engineering, Yuan-Ze University, Jung-Li City 320, Taiwan

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Genome Biology 2003, 4:R29 doi:10.1186/gb-2003-4-4-r29

Published: 14 March 2003

Abstract

ProSplicer is a database of putative alternative splicing information derived from the alignment of proteins, mRNA sequences and expressed sequence tags (ESTs) against human genomic DNA sequences. Proteins, mRNA and ESTs provide valuable evidence that can reveal splice variants of genes. The alternative splicing information in the database can help users investigate the alternative splicing and tissue-specific expression of genes.