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The role of DNA sequence in centromere formation

Jonathan C Lamb and James A Birchler*

Genome Biology 2003, 4:214 doi:10.1186/gb-2003-4-5-214

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Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes

Brenda R Grimes, Jennifer Babcock, M Katharine Rudd, Brian Chadwick, Huntington F Willard Genome Biology 2004, 5:R89 (27 October 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

An assay of the formation of heterochromatin and euchromatin on de novo human artificial chromosomes containing alpha satellite DNA revealed that only a small amount of heterochromatin may be required for centromere function and that replication late in S phase is not a requirement for centromere function.

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What's in a centromere?

Jonathan C Lamb, James Theuri, James A Birchler Genome Biology 2004, 5:239 (17 August 2004)

Abstract | Full text | PDF | PubMed | Editor’s summary

The complete sequence of rice centromere 8 reveals a small amount of centromere-specific satellite sequence in blocks interrupted by retrotransposons and other repetitive DNA, in an arrangement that is similar in size and content to other centromeres of multicellular eukaryotes.

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