This article has not been peer reviewed.
DAVID: Database for Annotation, Visualization, and Integrated Discovery
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* Corresponding author: Glynn Dennis GDennis@niaid.nih.gov
Genome Biology 2003, 4:P3 doi:10.1186/gb-2003-4-5-p3
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Willeke MC van Roon-Mom, Barry A Pepers, Peter AC 't Hoen, Carola ACM Verwijmeren, Johan T den Dunnen, Josephine C Dorsman, GertJan B van Ommen BMC Molecular Biology 2008, 9:84 (9 October 2008) |
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Monika Ray, Jianhua Ruan, Weixiong Zhang Genome Biology 2008, 9:R148 (8 October 2008) Analysis of microarray data reveals extensive links between Alzheimer’s disease and cardiovascular diseases. |
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Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes Maurizio Zuccotti, Valeria Merico, Lucia Sacchi, Michele Bellone, Thore C Brink, Riccardo Bellazzi, Mario Stefanelli, Carlo Redi, Silvia Garagna, James Adjaye BMC Developmental Biology 2008, 8:97 (6 October 2008) |
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Chris Cheadle, Maria Nesterova, Tonya Watkins, Kathleen C Barnes, John C Hall, Antony Rosen, Kevin G Becker, Yoon S Cho-Chung BMC Medical Genomics 2008, 1:43 (26 September 2008) Overexpression of the regulatory subunit of cAMP-dependent protein kinase (PKA) in ovarian cancer cells causes hyperproliferation for the RI isoform and differentiation for RII, suggesting that PKA may be pivotal in disease progression.
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Presenting and exploring biological pathways with PathVisio Martijn P van Iersel, Thomas Kelder, Alexander R Pico, Kristina Hanspers, Susan Coort, Bruce R Conklin, Chris Evelo BMC Bioinformatics 2008, 9:399 (25 September 2008) |
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Tali Eilon, Itamar Barash BMC Cancer 2008, 8:270 (24 September 2008) |
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Sami Kilpinen, Reija Autio, Kalle Ojala, Kristiina Iljin, Elmar Bucher, Henri Sara, Tommi Pisto, Matti Saarela, Rolf I Skotheim, Mari Björkman, John-Patrick Mpindi, Saija Haapa-Paananen, Paula Vainio, Henrik Edgren, Maija Wolf, Jaakko Astola, Matthias Nees, Sampsa Hautaniemi, Olli Kallioniemi Genome Biology 2008, 9:R139 (19 September 2008) A method for the comparison of mRNA expression levels of most human genes across gene expression array experiments, and a database of the results, are presented. |
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SQUAT: A web tool to mine human, murine and avian SAGE data Johan Leyritz, Stéphane Schicklin, Sylvain Blachon, Céline Keime, Céline Robardet, Jean-François Boulicaut, Jérémy Besson, Ruggero G Pensa, Olivier Gandrillon BMC Bioinformatics 2008, 9:378 (18 September 2008) |
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Stefano Moretti, Danitsja van Leeuwen, Hans Gmuender, Stefano Bonassi, Joost van Delft, Jos Kleinjans, Fioravante Patrone, Domenico Merlo BMC Bioinformatics 2008, 9:361 (2 September 2008) |
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Mikhail G Dozmorov, Kimberly D Kyker, Paul J Hauser, Ricardo Saban, David D Buethe, Igor Dozmorov, Michael B Centola, Daniel J Culkin, Robert E Hurst BMC Bioinformatics 2008, 9(Suppl 9):S4 (12 August 2008) |
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Wei Jiang, Xia Li, Shaoqi Rao, Lihong Wang, Lei Du, Chuanxing Li, Chao Wu, Hongzhi Wang, Yadong Wang, Baofeng Yang BMC Systems Biology 2008, 2:72 (10 August 2008) |
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Richard C McEachin, Benjamin J Keller, Erika FH Saunders, Melvin G McInnis BioData Mining 2008, 1:2 (17 July 2008) |
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Christina Yau, Christopher C Benz Breast Cancer Research 2008, 10:R61 (17 July 2008) An investigation into the effect of oxidative stress on estrogen and estrogen receptor-regulated gene expression identified a subset of oxidant-sensitive genes associated with poor prognosis in ER+ primary breast cancer.
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Kurtis Eisermann, Sunpreet Tandon, Anton Bazarov, Adina Brett, Gail Fraizer, Helen Piontkivska BMC Genomics 2008, 9:337 (16 July 2008) |
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Xia Chen, Shuang Liang, WenLing Zheng, ZhiJun Liao, Tao Shang, WenLi Ma BMC Genomics 2008, 9:322 (7 July 2008) |
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Masato Yoneda, Kikuko Hotta, Yuichi Nozaki, Hiroki Endo, Takashi Uchiyama, Hironori Mawatari, Hiroshi Iida, Shingo Kato, Kunihiro Hosono, Koji Fujita, Kyoko Yoneda, Hirokazu Takahashi, Hiroyuki Kirikoshi, Noritoshi Kobayashi, Masahiko Inamori, Yasunobu Abe, Kensuke Kubota, Satoru Saito, Shiro Maeyama, Koichiro Wada, Atsushi Nakajima BMC Gastroenterology 2008, 8:27 (27 June 2008) |
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Rob Jelier, Peter AC 't Hoen, Ellen Sterrenburg, Johan T den Dunnen, Gert-Jan B van Ommen, Jan A Kors, Barend Mons BMC Bioinformatics 2008, 9:291 (24 June 2008) |
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Florent Baty, Daniel Jaeger, Frank Preiswerk, Martin M Schumacher, Martin H Brutsche BMC Bioinformatics 2008, 9:289 (20 June 2008) |
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Michael J Boedigheimer, Russell D Wolfinger, Michael B Bass, Pierre R Bushel, Jeff W Chou, Matthew Cooper, J Christopher Corton, Jennifer Fostel, Susan Hester, Janice S Lee, Fenglong Liu, Jie Liu, Hui-Rong Qian, John Quackenbush, Syril Pettit, Karol L Thompson BMC Genomics 2008, 9:285 (12 June 2008) An inter-laboratory meta-analysis of more than 500 microarrays from the liver and kidney of control rats defined key sources of variability in control animals and will aid in the efficient design of future toxicogenomics experiments.
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Bent Honoré, Søren Buus, Mogens H Claësson Proteome Science 2008, 6:18 (10 June 2008) |
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Functional characterization of endogenous siRNA target genes in Caenorhabditis elegans Suvi Asikainen, Liisa Heikkinen, Garry Wong, Markus Storvik BMC Genomics 2008, 9:270 (3 June 2008) |
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Jacob G Bundy, Jasmin K Sidhu, Faisal Rana, David J Spurgeon, Claus Svendsen, Jodie F Wren, Stephen R Stürzenbaum, A John Morgan, Peter Kille BMC Biology 2008, 6:25 (3 June 2008) The toxic effects of chemical contaminants like copper on a key indicator organism, the earthworm, can be monitored by combining metabolomics and transcriptomics, a systems ecotoxicology approach that provides detailed molecular information about adaptation to soil pollutants.
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Wing-Cheong Wong, Marie Loh, Frank Eisenhaber Biology Direct 2008, 3:23 (3 June 2008) |
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Hector R Wong, Kelli Odoms, Bhuvaneswari Sakthivel BMC Immunology 2008, 9:24 (30 May 2008) |
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Improving the power for detecting overlapping genes from multiple DNA microarray-derived gene lists Xutao Deng, Jun Xu, Charles Wang BMC Bioinformatics 2008, 9(Suppl 6):S14 (28 May 2008) |
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Genomic analysis of post-mating changes in the honey bee queen (Apis mellifera) Sarah D Kocher, Freddie-Jeanne Richard, David R Tarpy, Christina M Grozinger BMC Genomics 2008, 9:232 (19 May 2008) |
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Michael D George, Jan Wehkamp, Robert J Kays, Christian M Leutenegger, Sadiah Sabir, Irina Grishina, Satya Dandekar, Charles L Bevins BMC Genomics 2008, 9:209 (5 May 2008) |
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Palaniappan Ramanathan, Ian C Martin, Margaret Gardiner-Garden, Peter C Thomson, Rosanne M Taylor, Christopher J Ormandy, Christopher Moran, Peter Williamson BMC Genomics 2008, 9:197 (29 April 2008) |
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Efthimia Karantzali, Herbert Schulz, Oliver Hummel, Norbert Hubner, AK Hatzopoulos, Androniki Kretsovali Genome Biology 2008, 9:R65 (4 April 2008) A gene profiling study of mouse embryonic stem cells treated with the histone deacetylase inhibitor trichostatin A shows that inhibition of histone deacetylases accelerates the early events of differentiation, by regulating the expression of pluripotency- and differentiation-associated in an opposite manner. |
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A sequence-based survey of the complex structural organization of tumor genomes Benjamin J Raphael, Stanislav Volik, Peng Yu, Chunxiao Wu, Guiqing Huang, Elena V Linardopoulou, Barbara J Trask, Frederic Waldman, Joseph Costello, Kenneth J Pienta, Gordon B Mills, Krystyna Bajsarowicz, Yasuko Kobayashi, Shivaranjani Sridharan, Pamela L Paris, Quanzhou Tao, Sarah J Aerni, Raymond P Brown, Ali Bashir, Joe W Gray, Jan-Fang Cheng, Pieter de Jong, Mikhail Nefedov, Thomas Ried, Hesed M Padilla-Nash, Colin C Collins Genome Biology 2008, 9:R59 (25 March 2008) Tumors and cancer cell lines were surveyed with end-sequencing profiling, yielding the largest available collection of sequence-ready tumor genome breakpoints and providing evidence that some rearrangements may be recurrent. |
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MADIBA: A web server toolkit for biological interpretation of Plasmodium and plant gene clusters Philip J Law, Clotilde Claudel-Renard, Fourie Joubert, Abraham I Louw, Dave K Berger BMC Genomics 2008, 9:105 (28 February 2008) |
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Merging microarray data from separate breast cancer studies provides a robust prognostic test Lei Xu, Aik Tan, Raimond L Winslow, Donald Geman BMC Bioinformatics 2008, 9:125 (27 February 2008) |
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Simple integrative preprocessing preserves what is shared in data sources Abhishek Tripathi, Arto Klami, Samuel Kaski BMC Bioinformatics 2008, 9:111 (21 February 2008) |
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Robert B Page, Stephen R Voss, Amy K Samuels, Jeramiah J Smith, Srikrishna Putta, Christopher K Beachy BMC Genomics 2008, 9:78 (11 February 2008) |
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Markus Thiersch, Wolfgang Raffelsberger, Rico Frigg, Marijana Samardzija, Andreas Wenzel, Olivier Poch, Christian Grimm BMC Genomics 2008, 9:73 (8 February 2008) |
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Characterization of a newly developed chicken 44K Agilent microarray Xianyao Li, Hsin-I Chiang, James Zhu, Scot E Dowd, Huaijun Zhou BMC Genomics 2008, 9:60 (31 January 2008) |
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David D Smith, Pål Sætrom, Ola Snøve, Cathryn Lundberg, Guillermo E Rivas, Carlotta Glackin, Garrett P Larson BMC Bioinformatics 2008, 9:63 (28 January 2008) |
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Scott H Robbins, Thierry Walzer, Doulaye Dembélé, Christelle Thibault, Axel Defays, Gilles Bessou, Huichun Xu, Eric Vivier, MacLean Sellars, Philippe Pierre, Franck R Sharp, Susan Chan, Philippe Kastner, Marc Dalod Genome Biology 2008, 9:R17 (24 January 2008) Genome-wide expression profiling of mouse and human leukocytes reveal conserved transcriptional programs of plasmacytoid or conventional dendritic cell subsets. |
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Coordinated evolution of co-expressed gene clusters in the Drosophila transcriptome Jason G Mezey, Sergey V Nuzhdin, Fangfei Ye, Corbin D Jones BMC Evolutionary Biology 2008, 8:2 (7 January 2008) |
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Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes Kriston L McGary, Insuk Lee, Edward M Marcotte Genome Biology 2007, 8:R258 (5 December 2007) Loss-of-function phenotypes of yeast genes can be predicted from the loss-of-function phenotypes of their neighbours in functional gene networks. This could potentially be applied to the prediction of human disease genes. |
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Prediction of synergistic transcription factors by function conservation Zihua Hu, Boyu Hu, James F Collins Genome Biology 2007, 8:R257 (5 December 2007) A new strategy is proposed for identifying synergistic transcription factors by function conservation, leading to the identification of 51 homotypic transcription-factor combinations. |
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Shuzhang Yang, Kai Wang, Otto Valladares, Sridhar Hannenhalli, Maja Bucan Genome Biology 2007, 8:R247 (20 November 2007) Microarray analysis shows that approximately 10% of transcripts in the mouse prefrontal cortex have diurnally regulated expression patterns. |
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J Christopher Bare, Paul T Shannon, Amy K Schmid, Nitin S Baliga BMC Bioinformatics 2007, 8:456 (19 November 2007) |
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Sanghyeon Kim, Kwang-Ho Choi, Ali Baykiz, Howard K Gershenfeld BMC Genomics 2007, 8:413 (12 November 2007) |
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Brad T Sherman, Da Huang, Qina Tan, Yongjian Guo, Stephan Bour, David Liu, Robert Stephens, Michael W Baseler, H Clifford Lane, Richard A Lempicki BMC Bioinformatics 2007, 8:426 (2 November 2007) |
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Large-scale analysis by SAGE reveals new mechanisms of v-erbA oncogene action Corinne Bresson, Celine Keime, Claudine Faure, Yann Letrillard, Maud Barbado, Sandra Sanfilippo, Najate Benhra, Olivier Gandrillon, Sandrine Gonin-Giraud BMC Genomics 2007, 8:390 (26 October 2007) |
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Computational selection and prioritization of candidate genes for Fetal Alcohol Syndrome Zané Lombard, Nicki Tiffin, Oliver Hofmann, Vladimir B Bajic, Winston Hide, Michèle Ramsay BMC Genomics 2007, 8:389 (25 October 2007) |
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BMDExpress: a software tool for the benchmark dose analyses of genomic data Longlong Yang, Bruce C Allen, Russell S Thomas BMC Genomics 2007, 8:387 (25 October 2007) |
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Simplified ontologies allowing comparison of developmental mammalian gene expression Adele Kruger, Oliver Hofmann, Piero Carninci, Yoshihide Hayashizaki, Winston Hide Genome Biology 2007, 8:R229 (25 October 2007) The Developmental eVOC ontologies presented are simplified orthogonal ontologies describing the temporal and spatial distribution of developmental human and mouse anatomy. |
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Hélène Coppin, Valérie Darnaud, Léon Kautz, Delphine Meynard, Marc Aubry, Jean Mosser, Maria Martinez, Marie-Paule Roth Genome Biology 2007, 8:R221 (18 October 2007) Gene expression profiling using microarrays of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading allowed the identification of transcriptional targets of the hemochromatosis-associated gene Hfe.
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Improved human disease candidate gene prioritization using mouse phenotype Jing Chen, Huan Xu, Bruce J Aronow, Anil G Jegga BMC Bioinformatics 2007, 8:392 (16 October 2007) |
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Characterization of oligopeptide patterns in large protein sets Anders Bresell, Bengt Persson BMC Genomics 2007, 8:346 (1 October 2007) |
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Linking microarray reporters with protein functions Stan Gaj, Arie van Erk, Rachel IM van Haaften, Chris TA Evelo BMC Bioinformatics 2007, 8:360 (26 September 2007) |
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Zhe Zhang, Dechang Chen, David A Fenstermacher BMC Genomics 2007, 8:331 (20 September 2007) |
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Guozhen Liu, Monica Uddin, Munirul Islam, Morris Goodman, Lawrence I Grossman, Roberto Romero, Derek E Wildman Source Code for Biology and Medicine 2007, 2:5 (18 September 2007) |
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Karol L Thompson, P Scott Pine, Barry A Rosenzweig, Yaron Turpaz, Jacques Retief BMC Biotechnology 2007, 7:57 (13 September 2007) |
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EDISA: extracting biclusters from multiple time-series of gene expression profiles Jochen Supper, Martin Strauch, Dierk Wanke, Klaus Harter, Andreas Zell BMC Bioinformatics 2007, 8:334 (12 September 2007) |
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Khaldoun Al-Romaih, Gino R Somers, Jane Bayani, Simon Hughes, Mona Prasad, Jean-Claude Cutz, Hui Xue, Maria Zielenska, Yuzhuo Wang, Jeremy A Squire Cancer Cell International 2007, 7:14 (10 September 2007) |
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Da Huang, Brad T Sherman, Qina Tan, Jack R Collins, W Gregory Alvord, Jean Roayaei, Robert Stephens, Michael W Baseler, H Clifford Lane, Richard A Lempicki Genome Biology 2007, 8:R183 (4 September 2007) The DAVID gene functional classification tool uses a novel fuzzy clustering algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. |
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Lawrence S Hon, Zemin Zhang Genome Biology 2007, 8:R166 (14 August 2007) A genome wide analysis of factors affecting repression of mRNAs by microRNAs reveals roles for 3'UTR length, the number of target sites on the mRNA and the distance between pairs of binding sites. |
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Randall Hulshizer, Eric M Blalock BMC Bioinformatics 2007, 8:240 (5 July 2007) |
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Morphine effects on striatal transcriptome in mice Michal Korostynski, Marcin Piechota, Dorota Kaminska, Wojciech Solecki, Ryszard Przewlocki Genome Biology 2007, 8:R128 (28 June 2007) Global transcriptional analysis of mouse striata following acute and chronic exposure to morphine reveals multiple physiological factors which may affect opioid-related phenotypes and implicates a number of gene networks, including glucocorticoid receptor regulated genes, in the response to this opioid. |
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Common molecular pathways involved in human CD133+/CD34+ progenitor cell expansion and cancer Oswaldo Okamoto, Ana Carolina SR Carvalho, Luciana C Marti, Ricardo Z Vêncio, Carlos A Moreira-Filho Cancer Cell International 2007, 7:11 (8 June 2007) |
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A functional map of NFκB signaling identifies novel modulators and multiple system controls Thomas A Halsey, Longlong Yang, John R Walker, John B Hogenesch, Russell S Thomas Genome Biology 2007, 8:R104 (6 June 2007) Using cell-based genomic screens and functional assays, positive and negative modulators of NFκB signaling were identified and mapped onto the known NFκB signaling cascade. |
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Understanding network concepts in modules Jun Dong, Steve Horvath BMC Systems Biology 2007, 1:24 (4 June 2007) |
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Markus Weniger, Julia C Engelmann, Jörg Schultz BMC Bioinformatics 2007, 8:179 (2 June 2007) |
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Boris Greber, Hans Lehrach, James Adjaye BMC Developmental Biology 2007, 7:46 (16 May 2007) |
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Yingchun Liu, Markus Ringnér Genome Biology 2007, 8:R77 (11 May 2007) A strategy for identifying cell signaling pathways whose deregulation result in an observed expression signature is presented. |
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Jennifer L Ingram, Aurita Antao-Menezes, Elizabeth A Turpin, Duncan G Wallace, James B Mangum, Linda J Pluta, Russell S Thomas, James C Bonner Respiratory Research 2007, 8:34 (25 April 2007) |
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Prathibha Ranganathan, Animesh Agrawal, Raghu Bhushan, Aravinda K Chavalmane, Ravi Kalathur, Takashi Takahashi, Paturu Kondaiah BMC Genomics 2007, 8:98 (11 April 2007) |
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Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes Michael Doss, Johannes Winkler, Shuhua Chen, Rita Hippler-Altenburg, Isaia Sotiriadou, Marcel Halbach, Kurt Pfannkuche, Huamin Liang, Herbert Schulz, Oliver Hummel, Norbert Hübner, Ruth Rottscheidt, Jürgen Hescheler, Agapios Sachinidis Genome Biology 2007, 8:R56 (11 April 2007) |