Table 1

Predicted and experimentally determined numbers of proteins present in mitochondria


Yeast
Reference
Human
Reference
Arabidopsis
Reference

Predictions*






Total
423
[29]
734
[17]
800
[20]

584
[17]
1,500
[30]



630
[11]




Prediction percentage
10-13%
[10,11]
10%
[9]
10%
[9]
Extrapolated
617-802

3,500

2,800








Experimental






Total
179
[13]
615
[7]
135
[14,15,18,20,31]

388
[32]





466
[12]




Experimental percentage§
2.9%

1.76%

0.48%


6.3%






7.6%






*Predictions of the number of mitochondrial proteins are from sequence homology, targeting sequences, phylogenetic profiling or extrapolation from a set of experimental values. Prediction percentage: the percentage of genes in the genome predicted to encode mitochondrial proteins from targeting analyses or phylogenetic profiles; Extrapolated: the total number of mitochondrial proteins predicted from the percentage value given and the genome size of each organism. §Experimental percentage: the percentage of the predicted proteome found in experimentally determined mitochondrial proteomes.

Heazlewood et al. Genome Biology 2003 4:218   doi:10.1186/gb-2003-4-6-218