Genome Biology
Volume 4
Issue 7 |
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CorrespondenceEST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in normal human and mouse tissuesNeil R Smalheiser  Department of Psychiatry, University of Illinois at Chicago, 1601 W. Taylor Street MC 912, Chicago, IL 60612, USA  author email corresponding author email
Genome Biology 2003,
4:403doi:10.1186/gb-2003-4-7-403
Subject areas: Genetics, Genome studies, Molecular biology, Bioinformatics Abstract
A significant population of expressed sequence tags (ESTs) encodes chimeric transcripts containing microRNA (miRNA) precursor sequences as well as pieces of adjacent mRNAs in sense orientation. These chimeric transcripts may potentially be involved in miRNA biosynthesis, and/or affect expression of adjacent mammalian mRNAs. | 
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