Genome Biology

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Phylogenetically and spatially conserved word pairs associated with gene-expression changes in yeasts

Derek Y Chiang1, Alan M Moses2, Manolis Kellis3, Eric S Lander4 and Michael B Eisen5,6*

Author Affiliations

1 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA

2 Graduate Group in Biophysics, University of California, Berkeley, CA 94720, USA

3 Whitehead/MIT Center for Genome Research, Department of Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

4 Whitehead/MIT Center for Genome Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

5 Department of Genome Sciences, Life Sciences Division, Ernest Orlando Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA 94720, USA

6 Center for Integrative Genomics and Division of Genetics and Development, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA

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Genome Biology 2003, 4:R43 doi:10.1186/gb-2003-4-7-r43

Published: 26 June 2003

Additional files

Additional data file 1:

A tab-delimited text list of 989 identified conserved word-pair templates

Format: TXT Size: 84KB Download file

Open Data

Additional data file 2:

A figure that shows that incorporation of conservation and word pairs provided more informative average expression profiles

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Additional data file 3:

A figure that shows that regression models using conserved word pairs represented better fits to genome-wide expression data

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Open Data

Additional data file 4:

The underlying data for Figure 4 that show associations between gene groups that share a conserved word-pair template with gene-expression changes

Format: ZIP Size: 42KB Download file

Open Data