Research
Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice
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* Corresponding author: Chad Creighton ccreight@umich.edu
1 Bioinformatics Program, Human Genetics, and Public Health, University of Michigan, Ann Arbor, MI 48109, USA
2 Department of Pediatrics and Communicable Diseases, Human Genetics, and Public Health, University of Michigan, Ann Arbor, MI 48109, USA
3 Department of Internal Medicine, Human Genetics, and Public Health, University of Michigan, Ann Arbor, MI 48109, USA
Genome Biology 2003, 4:R46 doi:10.1186/gb-2003-4-7-r46
Published: 23 June 2003Additional files
Additional data file 1:
Expression datasets of the cell culture and xenograft profiles
Format: TXT Size: 762KB Download file
Additional data file 2:
The scale-normalized means prior to quantile normalization, p-values from the 'present' test, a sheet of data from 60 control probe-sets on the Affymetrix chips, and data from the mouse lung tissue control profile
Format: XLS Size: 4.6MB Download file
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Additional data file 3:
The search results for significantly enriched classes for GO annotation for genes found to significantly differ between tumors and cell cultures for a given cell line
Format: XLS Size: 5.6MB Download file
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Additional data file 4:
The search results for significantly enriched classes for MeSH term literature associations for genes found to significantly differ between tumors and cell cultures for a given cell line
Format: XLS Size: 13.4MB Download file
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Additional data file 5:
The values used in the classifications of cell culture lineage using xenograft tumor profiles, together with the classification results, which correctly predicted the lineage of all six cell culture profiles
Format: XLS Size: 4.5MB Download file
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