Genome Biology

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Comparative genomics of archaea: how much have we learned in six years, and what's next?

Kira S Makarova and Eugene V Koonin*

Genome Biology 2003, 4:115 doi:10.1186/gb-2003-4-8-115

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Genomic context analysis in Archaea suggests previously unrecognized links between DNA replication and translation

Jonathan Berthon, Diego Cortez, Patrick Forterre Genome Biology 2008, 9:R71 (9 April 2008)

Specific functional interactions of proteins involved in DNA replication and/or DNA repair or transcription might occur in Archaea, suggesting a previously unrecognized regulatory network coupling DNA replication and translation, which might also exist in Eukarya.

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Clusters of orthologous genes for 41 archaeal genomes and implications for evolutionary genomics of archaea

Kira S Makarova, Alexander V Sorokin, Pavel S Novichkov, Yuri I Wolf, Eugene V Koonin Biology Direct 2007, 2:33 (27 November 2007)

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High precision multi-genome scale reannotation of enzyme function by EFICAz

Adrian K Arakaki, Weidong Tian, Jeffrey Skolnick BMC Genomics 2006, 7:315 (13 December 2006)

Research article   Open Access

Evolution of a microbial nitrilase gene family: a comparative and environmental genomics study

Mircea Podar, Jonathan R Eads, Toby H Richardson BMC Evolutionary Biology 2005, 5:42 (6 August 2005)

Differences between the functions of microbial nitrilases are associated with the genetic neighbourhood of individual subfamily members, suggesting that nitrilases have been recruited to new metabolic pathways following gene duplication and neofunctionalization.

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Deciphering structure and topology of conserved COG2042 orphan proteins

Jean Armengaud, Alain Dedieu, Olivier Solques, Jean-Luc Pellequer, Eric Quemeneur BMC Structural Biology 2005, 5:3 (8 February 2005)

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Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns

Galina V Glazko, Arcady R Mushegian Genome Biology 2004, 5:R32 (27 April 2004)

A hierarchy of 3,688 phyletic patterns was characterized encompassing more than 5,000 known protein-coding genes from 66 complete microbial genomes. The results indicate that gene loss and displacement has occurred in the evolution of most pathways.

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Archaeal phylogeny based on proteins of the transcription and translation machineries: tackling the Methanopyrus kandleri paradox

Céline Brochier, Patrick Forterre, Simonetta Gribaldo Genome Biology 2004, 5:R17 (26 February 2004)

This article presents a phylogenetic analysis of the Archea based on sets of transcription and translation proteins. The phylogenies shed light on the evolutionary position of Methanopyrus kandleri.