Table 1

Chromosomal regions implicated in panic disorder, phobias and anxiety traits

Phenotype
1q
3q
4q21
4q34
7p
8q
9q
10q
11p
12q
13q
14p
22q
Reference

Panic disorder (PD)
+++
+


+
++
++++


+
++++
+
++++
[13,15,16,19]

+
+

+
++




++*



[11,17]

++








++



[15,16]
Agoraphobia (AG)
-
++
+





++




[13]


++++*











[13]
PD + AG








+


+

[13]
Specific Phobia
+
++

+

++

+
+


+++

[14]


+++*











[14]
PD + anxiety
+

+



++
++

+



[17,19]
Neuroticism
++++


++++
++++




++++
++++


[12]
Mouse QTL
++++








++++

++++
+++
[17,27]

*One family. Human equivalents of mouse QTLs. The number of + signs indicates the approximate relative significance of the linkage.

Villafuerte and Burmeister Genome Biology 2003 4:224   doi:10.1186/gb-2003-4-8-224