Figure 4.

In situ gene displacement in the NADH-ubiquinone oxidoreductase operon in Halobacterium. (a) Organization of the NADH-ubiquinone oxidoreductase operon in selected archaeal and bacterial genomes. COG0838 - NADH:ubiquinone oxidoreductase subunit 3 (chain A), COG3077 - DNA-damage-inducible protein J, COG0852 - NADH:ubiquinone oxidoreductase 27 kD subunit, COG0649 - NADH:ubiquinone oxidoreductase 49 kD subunit 7, COG1905 - NADH:ubiquinone oxidoreductase 24 kD subunit, COG1894 - NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit, COG1034 - NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G), COG1005 - NADH:ubiquinone oxidoreductase subunit 1 (chain H), COG1143 - Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I), COG0839 - NADH:ubiquinone oxidoreductase subunit 6 (chain J), COG0713 - NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K), COG1009 - NADH:ubiquinone oxidoreductase subunit 5 (chain L), COG1008 - NADH:ubiquinone oxidoreductase subunit 4 (chain M), COG1007 - NADH:ubiquinone oxidoreductase subunit 2 (chain N). The designations are as in Figure 1a. For species abbreviations, see Materials and methods. (b-d) Unrooted maximum-likelihood tree for NuoH (b), NuoI (c) and NuoJ (d); the designations are as in Figure 1b.